{"product_id":"abcam-ab108199","title":"Abcam, ab108199, Anti-ARFRP1\/ARP antibody [EPR3899]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal ARFRP1\/ARP antibody. Suitable for WB, ICC\/IF and reacts with Human samples. Cited in 3 publications.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR3899,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WB, ICC\/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.05% Sodium azideConstituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 0.1% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Storage information-Stable for 12 months at -20°C\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nThe target ARFRP1 also known as ARP functions mechanistically as a small GTPase belonging to the ARF family. This protein possesses an approximate molecular mass of 20 kDa. It is ubiquitously expressed in various tissues exhibiting a significant presence in the cytoplasm and membrane compartments. ARFRP1 plays a role in regulating membrane trafficking and lipid metabolism influencing the formation and function of vesicles within the cell.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nARFRP1 participates in intracellular vesicle transport and is critical for maintaining cellular homeostasis. It forms part of a complex that interacts with other proteins involved in vesicular traffic affecting cargo selection and vesicle formation. ARFRP1 contributes to maintaining the structural integrity of the Golgi apparatus and endosomes influencing the distribution of proteins and lipids across cellular compartments.\u003cbr\u003e\nPathways\u003cbr\u003e\nARFRP1 features prominently in pathways related to endocytic and exocytic transport. In the context of membrane traffic it closely interacts with proteins such as ARL1 and ARL4 which also play roles in these pathways. ARFRP1 influences the functioning of these pathways contributing to both protein recycling and secretion processes.\u003cbr\u003e\nThe dysfunction of ARFRP1 associates with Charcot-Marie-Tooth disease and Bardet-Biedl syndrome. In these conditions ARFRP1 may interact with related proteins like ARF6 impacting cell signaling and membrane dynamics. These interactions can lead to defects in cell transport mechanisms further elucidating the role of ARFRP1 in pathological states.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850415820969,"sku":"ab108199","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab108199","provider":"Iright","version":"1.0","type":"link"}