{"product_id":"abcam-ab112894","title":"Abcam, ab112894, HRP Anti-LGB antibody","description":"\u003cp\u003eSize: 1mg\u003cbr\u003e\nRabbit Polyclonal LGB antibody - conjugated to HRP. Suitable for ICC, ELISA, WB, IHC-P and reacts with Cow samples. Cited in 1 publication. Immunogen corresponding to Native Full Length Protein corresponding to Cow LGB.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nConjugation:HRP,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Cow,\u003cbr\u003e\nApplications:WB, IHC-P, ICC, ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Native Full Length Protein corresponding to Cow LGB.P02754\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Purification notes-Antiserum was solid phase adsorbed to ensure specificity. ab112894 was isolated by affinity chromatography using antigen coupled to agarose beads and conjugated to horseradish peroxidase (HRP)., Storage buffer-pH: 6.8 - 7.4Preservative: 0.05% CMIT\/MIT based preservativeConstituents: 0.2% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nLGB also known as beta-lactoglobulin is a small globular protein with a mass of approximately 18 kDa. It is predominantly expressed in the milk of ruminants including cows sheep and goats. The protein is considered a major whey protein and it forms small soluble aggregates in milk. LGB exhibits the ability to bind hydrophobic molecules which suggests it plays a role in transport or storage of lipophilic molecules within milk.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThis protein functions in the stabilization and transport of fatty acids and other hydrophobic molecules. LGB does not form part of a larger protein complex but can dimerize under certain conditions. It has a notable affinity for binding ligands particularly vitamins and flavor compounds which may significantly influence nutritional and sensory qualities of milk and dairy products.\u003cbr\u003e\nPathways\u003cbr\u003e\nLGB's functional role suggests involvement in metabolic and nutritional pathways related to lipid transport and digestion. It has an indirect relationship with the digestive enzyme lipase as LGB-bound lipids become more accessible for digestion. Furthermore its lipid-binding characteristics support its involvement with fatty acid metabolism playing a role similar to serum albumin in circulating lipid constituents.\u003cbr\u003e\nLGB is most commonly implicated in food allergies particularly cow's milk allergy. Its antigenic properties make it a significant allergen in humans especially young children. Through this context LGB relates to the immune response proteins such as immunoglobulin E (IgE) which mediate allergic reactions. Understanding these interactions between LGB and immune components remains essential for developing hypoallergenic milk products.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46860515442857,"sku":"ab112894","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab112894","provider":"Iright","version":"1.0","type":"link"}