{"product_id":"abcam-ab120026","title":"Abcam, ab120026, N-Desmethyl clozapine (Normethylclozapine), Clozapine metabolite. M1 agonist. D2\/D3 agonist.","description":"\u003cp\u003eSize: 10mg \/ 50mg\u003cbr\u003e\nMW 312.8 Da, Purity \u0026gt;99%. Brain penetrant metabolite of the atypical antipsychotic clozapine. Broad range of actions. Potent allosteric M1 partial agonist (IC50 = 55 nM for inhibition of [3H]-NMS binding). D2\/D3 partial agonist. Also displays affinity at 5-HT1 and 5-HT2.\u003cbr\u003e\nKey facts\u003cbr\u003e\nPurity:\u0026gt;99%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:312.8 Da,\u003cbr\u003e\nMolecular formula:C17H17ClN4,\u003cbr\u003e\nPubChem:2820,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 100 mM,\u003cbr\u003e\nBiochemical name:CID 2820,\u003cbr\u003e\nBiological description:Brain penetrant metabolite of the atypical antipsychotic clozapine. Broad range of actions. Potent allosteric M1 partial agonist (IC50 = 55 nM for inhibition of [3H]-NMS binding). D2\/D3 partial agonist. Also displays affinity at 5-HT1 and 5-HT2.,\u003cbr\u003e\nCanonical smiles:C1CN(CCN1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl,\u003cbr\u003e\nIsomeric smiles:C1CN(CCN1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl,\u003cbr\u003e\nInChi:InChI=1S\/C17H17ClN4\/c18-12-5-6-15-16(11-12)21-17(22-9-7-19-8-10-22)13-3-1-2-4-14(13)20-15\/h1-6,11,19,21H,7-10H2,\u003cbr\u003e\nInChiKey:HESZUPIXRNZIOI-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:3-chloro-6-piperazin-1-yl-5H-benzo[b][1,4]benzodiazepine\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847485804713,"sku":"ab120026","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab120026","provider":"Iright","version":"1.0","type":"link"}