{"product_id":"abcam-ab120812","title":"Abcam, ab120812, RS 102895 hydrochloride, CCR2 receptor antagonist","description":"\u003cp\u003eSize: 10mg \/ 50mg\u003cbr\u003e\nMW 426.9 Da, Purity \u0026gt;99%. Selective CCR2 receptor antagonist (IC 50  values are 360 nM and 17.8 μM at CCR2 and CCR1 receptors, respectively). Inhibits MCP-1 and MCP-3 stimulated calcium influx (IC 50  values are 32 and 130 nM, respectively). Active  in vivo .\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:300815-41-2,\u003cbr\u003e\nPurity:\u0026gt;99%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:426.9 Da,\u003cbr\u003e\nMolecular formula:C21H22ClF3N2O2,\u003cbr\u003e\nPubChem:16759153,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 50 mM,\u003cbr\u003e\nBiochemical name:RS 102895 hydrochloride,\u003cbr\u003e\nBiological description:Selective CCR2 receptor antagonist (IC50 values are 360 nM and 17.8 μM at CCR2 and CCR1 receptors, respectively). Inhibits MCP-1 and MCP-3 stimulated calcium influx (IC50 values are 32 and 130 nM, respectively). Active in vivo.,\u003cbr\u003e\nCanonical smiles:C1CN(CCC12C3=CC=CC=C3NC(=O)O2)CCC4=CC=C(C=C4)C(F)(F)F.Cl,\u003cbr\u003e\nInChi:InChI=1S\/C21H21F3N2O2.ClH\/c22-21(23,24)16-7-5-15(6-8-16)9-12-26-13-10-20(11-14-26)17-3-1-2-4-18(17)25-19(27)28-20;\/h1-8H,9-14H2,(H,25,27);1H,\u003cbr\u003e\nInChiKey:KRRISOFSWVKYBF-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one;hydrochloride\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847420006569,"sku":"ab120812","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab120812","provider":"Iright","version":"1.0","type":"link"}