{"product_id":"abcam-ab120885","title":"Abcam, ab120885, PIT-1, PIP3\/protein binding inhibitor","description":"\u003cp\u003eSize: 10mg \/ 50mg\u003cbr\u003e\nMW 351.76 g\/mol, Purity \u0026gt;98%. PIP3\/protein binding inhibitor. Specifically disrupts PIP3\/Akt PH domain binding (IC 50  = 31 μM); suppresses PI3K-PDK1-Akt-dependent phosphorylation. Reduces cell viability and induces apoptosis in PTEN-deficient U87MG glioblastoma cells (IC 50  = 37 μM). 3,5-Dimethyl PIT-1 (ab120884) also available.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:53501-41-0,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:351.76 g\/mol,\u003cbr\u003e\nMolecular formula:C14H10ClN3O4S,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 20 mg\/mlSoluble in ethanol to 0.5 mg\/ml,\u003cbr\u003e\nBiological description:PIP3\/protein binding inhibitor. Specifically disrupts PIP3\/Akt PH domain binding (IC50 = 31 μM); suppresses PI3K-PDK1-Akt-dependent phosphorylation. Reduces cell viability and induces apoptosis in PTEN-deficient U87MG glioblastoma cells (IC50 = 37 μM). 3,5-Dimethyl PIT-1 (ab120884) also available.,\u003cbr\u003e\nCanonical smiles:O=C(NC(NC1=C(O)C(CL)=CC([N+]([O-])=O)=C1)=S)C2=CC=CC=C2,\u003cbr\u003e\nIUPAC Name:N-[[(3-Chloro-2-hydroxy-5-nitrophenyl)amino]thioxomethyl]benzamide\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847448481961,"sku":"ab120885","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab120885","provider":"Iright","version":"1.0","type":"link"}