{"product_id":"abcam-ab138499","title":"Abcam, ab138499, Anti-ZNF575 antibody [EPR9027]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal ZNF575 antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 1 publication.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR9027,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WB, Flow Cyt (Intra)See reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nThe ZNF575 protein also known as Zinc Finger Protein 575 weighs approximately 65 kDa. It contains zinc finger motifs that facilitate DNA binding. These motifs are involved in the regulation of gene transcription. Researchers have detected ZNF575 expression mainly in the brain and reproductive tissues indicating its function may concentrate in these regions.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nZNF575 participates in the regulation of gene expression. It acts as a transcription factor directly influencing the activity of various genes. Although not consistently reported as being part of large molecular complexes ZNF575 can interact with other transcription factors and cofactors. This interaction suggests a role in modulating developmental and cell differentiation processes.\u003cbr\u003e\nPathways\u003cbr\u003e\nZNF575 interacts with key pathways like the Wnt signaling and p53 pathway. The Wnt signaling pathway controls critical aspects of cell fate including cellular migration and organogenesis. Its role in the p53 pathway links ZNF575 to the regulation of cell cycle and apoptosis through associations with other proteins like beta-catenin and various p53-regulated genes.\u003cbr\u003e\nThe presence of ZNF575 has implications for neurodegenerative diseases and certain cancers. Misregulation of ZNF575 can influence neuronal function potentially contributing to conditions like Alzheimer's disease. In cancer altered expression of ZNF575 can be associated with tumorigenesis through its interaction with the p53 protein affecting cell growth and survival.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850224095401,"sku":"ab138499","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab138499","provider":"Iright","version":"1.0","type":"link"}