{"product_id":"abcam-ab141013","title":"Abcam, ab141013, RG 108, non-nucleoside DNA methyltransferase inhibitor (DNMT)","description":"\u003cp\u003eSize: 5mg \/ 10mg \/ 50mg\u003cbr\u003e\nMW 334.3 Da, Purity \u0026gt;99%. Novel, non-nucleoside DNA methyltransferase (DNMT) inhibitor, capable of interacting with the DNMT1 active site (IC 50  = 115 nM). Inhibits DNA methylation in human cancer cell lines. Reactivates several epigenetically silenced tumour suppressor genes  in vitro . Capable of enhancing the efficiency of induced pluripotent stem cell (iPS) generation.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:48208-26-0,\u003cbr\u003e\nPurity:\u0026gt;99%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:334.3 Da,\u003cbr\u003e\nMolecular formula:C19H14N2O4,\u003cbr\u003e\nPubChem:702558,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nBiochemical name:N-Phthalyl-L-tryptophan,\u003cbr\u003e\nBiological description:Novel, non-nucleoside DNA methyltransferase (DNMT) inhibitor, capable of interacting with the DNMT1 active site (IC50 = 115 nM). Inhibits DNA methylation in human cancer cell lines. Reactivates several epigenetically silenced tumour suppressor genes in vitro. Capable of enhancing the efficiency of induced pluripotent stem cell (iPS) generation.,\u003cbr\u003e\nCanonical smiles:C1=CC=C2C(=C1)C(=O)N(C2=O)C(CC3=CNC4=CC=CC=C43)C(=O)O,\u003cbr\u003e\nIsomeric smiles:C1=CC=C2C(=C1)C(=O)N(C2=O)[C@@H](CC3=CNC4=CC=CC=C43)C(=O)O,\u003cbr\u003e\nInChi:InChI=1S\/C19H14N2O4\/c22-17-13-6-1-2-7-14(13)18(23)21(17)16(19(24)25)9-11-10-20-15-8-4-3-5-12(11)15\/h1-8,10,16,20H,9H2,(H,24,25)\/t16-\/m0\/s1,\u003cbr\u003e\nInChiKey:HPTXLHAHLXOAKV-INIZCTEOSA-N,\u003cbr\u003e\nIUPAC Name:(2S)-2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847422136489,"sku":"ab141013","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab141013","provider":"Iright","version":"1.0","type":"link"}