{"product_id":"abcam-ab141412","title":"Abcam, ab141412, clasto-Lactacystin beta-lactone, 20S proteasome inhibitor","description":"\u003cp\u003eSize: 100µg\u003cbr\u003e\nMW 213.23 Da, Purity \u0026gt;95%. Potent, irreversible and cell-permeable 20S proteasome inhibitor (IC 50  = 50 nM). Active metabolite of lactacystin (ab141411). Inhibits cell-cycle progression in cancer cells. Antitumor agent. Active  in vivo  and  in vitro .\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:154226-60-5,\u003cbr\u003e\nPurity:\u0026gt;95%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:213.23 Da,\u003cbr\u003e\nMolecular formula:C10H15NO4,\u003cbr\u003e\nPubChem:9794358,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 75 mMSoluble in water to 10 mM,\u003cbr\u003e\nBiochemical name:Clasto-lactacystin beta-lactone,\u003cbr\u003e\nBiological description:Potent, irreversible and cell-permeable 20S proteasome inhibitor (IC50 = 50 nM). Active metabolite of lactacystin (ab141411). Inhibits cell-cycle progression in cancer cells. Antitumor agent. Active in vivo and in vitro.,\u003cbr\u003e\nCanonical smiles:CC1C2C(C(=O)O2)(NC1=O)C(C(C)C)O,\u003cbr\u003e\nIsomeric smiles:C[C@@H]1[C@H]2[C@](C(=O)O2)(NC1=O)[C@H](C(C)C)O,\u003cbr\u003e\nInChi:InChI=1S\/C10H15NO4\/c1-4(2)6(12)10-7(15-9(10)14)5(3)8(13)11-10\/h4-7,12H,1-3H3,(H,11,13)\/t5-,6+,7+,10-\/m1\/s1,\u003cbr\u003e\nInChiKey:FWPWHHUJACGNMZ-NBBQQVJHSA-N,\u003cbr\u003e\nIUPAC Name:(1R,4R,5S)-1-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called 1710 Clasto-Lactacystin ß-lactone. 1710-100 is the same size as the 100 μg size of ab141412.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847426232489,"sku":"ab141412","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab141412","provider":"Iright","version":"1.0","type":"link"}