{"product_id":"abcam-ab141434","title":"Abcam, ab141434, S3I-201, STAT3 inhibitor","description":"\u003cp\u003eSize: 5mg \/ 25mg\u003cbr\u003e\nMW 365.4 Da, Purity \u0026gt;97%. Selective STAT3 inhibitor (IC 50  values are 86, 160, 166 and \u0026gt;300 μM for STAT3.STAT3, STAT1.STAT3 STAT1.STAT1 and STAT5.STAT5 DNA binding activity respectively). Suppresses fibronectin, α-SMA, and collagen I expression. Shows apoptotic antiproliferative effects. Shows anti-inflammatory and analgesic effects  in vivo.  Centrally active.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:501919-59-1,\u003cbr\u003e\nPurity:\u0026gt;97%,\u003cbr\u003e\nMolecular weight:365.4 Da,\u003cbr\u003e\nMolecular formula:C16H15NO7S,\u003cbr\u003e\nPubChem:252682,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 25 mM,\u003cbr\u003e\nBiochemical name:2-Hydroxy-4-(2-(tosyloxy)acetamido)benzoic acid,\u003cbr\u003e\nBiological description:Selective STAT3 inhibitor (IC50 values are 86, 160, 166 and \u0026gt;300 μM for STAT3.STAT3, STAT1.STAT3 STAT1.STAT1 and STAT5.STAT5 DNA binding activity respectively). Suppresses fibronectin, α-SMA, and collagen I expression. Shows apoptotic antiproliferative effects. Shows anti-inflammatory and analgesic effects in vivo. Centrally active.,\u003cbr\u003e\nCanonical smiles:CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O,\u003cbr\u003e\nInChi:InChI=1S\/C16H15NO7S\/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11\/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21),\u003cbr\u003e\nInChiKey:HWNUSGNZBAISFM-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:2-hydroxy-4-[[2-(4-methylphenyl)sulfonyloxyacetyl]amino]benzoic acid\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called 1775 Stat3 Inhibitor I, S3I-201. 1775-25 is the same size as the 25 mg size of ab141434.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847431180457,"sku":"ab141434","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab141434","provider":"Iright","version":"1.0","type":"link"}