{"product_id":"abcam-ab142074","title":"Abcam, ab142074, PAC-1, caspase-3 activator","description":"\u003cp\u003eSize: 10mg\u003cbr\u003e\nMW 392.5 Da, Purity \u0026gt;95%. Potent caspase-3 activator (IC 50  = 220 nM). Also activates caspase-7 (IC 50  = 4.5 μM). Proapoptotic  in vitro . Anticancer activity  in vivo . Orally active.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:315183-21-2,\u003cbr\u003e\nPurity:\u0026gt;95%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:392.5 Da,\u003cbr\u003e\nMolecular formula:C23H28N4O2,\u003cbr\u003e\nPubChem:6851947,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in water to 5 mMSoluble in DMSO to 25 mM,\u003cbr\u003e\nBiochemical name:CID 6851947,\u003cbr\u003e\nBiological description:Potent caspase-3 activator (IC50 = 220 nM). Also activates caspase-7 (IC50 = 4.5 μM). Proapoptotic in vitro. Anticancer activity in vivo. Orally active.,\u003cbr\u003e\nCanonical smiles:C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)C1=O,\u003cbr\u003e\nIsomeric smiles:C=CCC1=CC=C\/C(=C\/NNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)\/C1=O,\u003cbr\u003e\nInChi:InChI=1S\/C23H28N4O2\/c1-2-7-20-10-6-11-21(23(20)29)16-24-25-22(28)18-27-14-12-26(13-15-27)17-19-8-4-3-5-9-19\/h2-6,8-11,16,24H,1,7,12-15,17-18H2,(H,25,28)\/b21-16-,\u003cbr\u003e\nInChiKey:XSGXRYNZNGUGEJ-PGMHBOJBSA-N,\u003cbr\u003e\nIUPAC Name:2-(4-benzylpiperazin-1-yl)-N'-[(Z)-(6-oxo-5-prop-2-enylcyclohexa-2,4-dien-1-ylidene)methyl]acetohydrazide\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called 1654 PAC-1. 1654-10 is the same size as the 10 mg size of ab142074.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847472140457,"sku":"ab142074","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab142074","provider":"Iright","version":"1.0","type":"link"}