{"product_id":"abcam-ab142096","title":"Abcam, ab142096, GW 2580, cFMS RTK inhibitor","description":"\u003cp\u003eSize: 5mg \/ 25mg\u003cbr\u003e\nMW 366.4 Da, Purity \u0026gt;99%. Selective cFMS (colony stimulating factor 1) RTK inhibitor. Inhibits monocyte growth  in vitro  (IC 50  = 0.2 μM) and LPS-induced TNF-α production  in vivo . Inhibits macrophage infiltration of the CNS. Orally active. Cell-permeable.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:870483-87-7,\u003cbr\u003e\nPurity:\u0026gt;99%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:366.4 Da,\u003cbr\u003e\nMolecular formula:C20H22N4O3,\u003cbr\u003e\nPubChem:11617559,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 100 mM,\u003cbr\u003e\nBiochemical name:5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine,\u003cbr\u003e\nBiological description:Selective cFMS (colony stimulating factor 1) RTK inhibitor. Inhibits monocyte growth in vitro (IC50 = 0.2 μM) and LPS-induced TNF-α production in vivo. Inhibits macrophage infiltration of the CNS. Orally active. Cell-permeable.,\u003cbr\u003e\nCanonical smiles:COC1=CC=C(C=C1)COC2=C(C=C(C=C2)CC3=CN=C(N=C3N)N)OC,\u003cbr\u003e\nInChi:InChI=1S\/C20H22N4O3\/c1-25-16-6-3-13(4-7-16)12-27-17-8-5-14(10-18(17)26-2)9-15-11-23-20(22)24-19(15)21\/h3-8,10-11H,9,12H2,1-2H3,(H4,21,22,23,24),\u003cbr\u003e\nInChiKey:MYQAUKPBNJWPIE-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847455854761,"sku":"ab142096","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab142096","provider":"Iright","version":"1.0","type":"link"}