{"product_id":"abcam-ab142464","title":"Abcam, ab142464, Tetrandrine, Calcium channel blocker","description":"\u003cp\u003eSize: 100mg \/ 500mg \/ 1g\u003cbr\u003e\nMW 622.7 Da, Purity \u0026gt;98%. Calcium channel blocker. (IC 50  values are 8 and 20 μM for L -type and T-type calcium channels respectively). Various pharmacological effects. Shows anti-inflammatory and antitumor activity. Inhibits osteoclast differentiation  in vivo.  Induces cell autophagy and ROS accumulation. Inhibits NF-κβ signaling.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:518-34-3,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nSource:Stephania tetrandra,\u003cbr\u003e\nMolecular weight:622.7 Da,\u003cbr\u003e\nMolecular formula:C38H42N2O6,\u003cbr\u003e\nPubChem:73078,\u003cbr\u003e\nNature:Native,\u003cbr\u003e\nSolubility:Soluble in ethanol to 5 mMSoluble in DMSO to 5 mM,\u003cbr\u003e\nBiochemical name:Tetrandrine,\u003cbr\u003e\nBiological description:Calcium channel blocker. (IC50 values are 8 and 20 μM for L -type and T-type calcium channels respectively). Various pharmacological effects. Shows anti-inflammatory and antitumor activity. Inhibits osteoclast differentiation in vivo. Induces cell autophagy and ROS accumulation. Inhibits NF-κβ signaling.,\u003cbr\u003e\nCanonical smiles:CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC,\u003cbr\u003e\nIsomeric smiles:CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC,\u003cbr\u003e\nInChi:InChI=1S\/C38H42N2O6\/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34\/h7-12,19-22,29-30H,13-18H2,1-6H3\/t29-,30-\/m0\/s1,\u003cbr\u003e\nInChiKey:WVTKBKWTSCPRNU-KYJUHHDHSA-N,\u003cbr\u003e\nIUPAC Name:(1S,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaene\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847425937577,"sku":"ab142464","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab142464","provider":"Iright","version":"1.0","type":"link"}