{"product_id":"abcam-ab142811","title":"Abcam, ab142811, BIO-acetoxime, GSK-3alpha\/beta inhibitor","description":"\u003cp\u003eSize: 1mg \/ 10mg\u003cbr\u003e\nMW 398.22 g\/mol, Purity \u0026gt;98%. Potent and selective GSK-3α\/β inhibitor (IC 50  values are 0.01, 2.4, 4.3 and 63 μM for GSK-3α\/β, CDK5\/p25, CDK2\/cyclin A and CDK1\/cyclin B respectively). Induces Wnt signaling. Inhibits CD8 +  T cell differentiation. Shows antiapoptotic effects.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:667463-85-6,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:398.22 g\/mol,\u003cbr\u003e\nMolecular formula:C18H12BrN3O3,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 25 mM,\u003cbr\u003e\nBiological description:Potent and selective GSK-3α\/β inhibitor (IC50 values are 0.01, 2.4, 4.3 and 63 μM for GSK-3α\/β, CDK5\/p25, CDK2\/cyclin A and CDK1\/cyclin B respectively). Induces Wnt signaling. Inhibits CD8+ T cell differentiation. Shows antiapoptotic effects.,\u003cbr\u003e\nIsomeric smiles:CC(=O)O\\N=C3\/C4CCCCC4N\/C3=C1\/C2CCC(BR)CC2NC1=O,\u003cbr\u003e\nInChi:InChI=1S\/C18H12BrN3O3\/c1-9(23)25-22-16-12-4-2-3-5-13(12)20-17(16)15-11-7-6-10(19)8-14(11)21-18(15)24\/h2-8,20H,1H3,(H,21,24)\/b17-15-,22-16+,\u003cbr\u003e\nInChiKey:MENDIXKFTXYTHJ-HPBPSMLHSA-N,\u003cbr\u003e\nIUPAC Name:3-[(3E)-3-[(Acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-2H-indol-2-one\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847465488553,"sku":"ab142811","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab142811","provider":"Iright","version":"1.0","type":"link"}