{"product_id":"abcam-ab144419","title":"Abcam, ab144419, CAY10572 (PHA-767491), Cdc7 and Cdk9 kinase inhibitor","description":"\u003cp\u003eSize: 5mg \/ 10mg \/ 50mg\u003cbr\u003e\nMW 249.69 Da, Purity \u0026gt;98%. Potent Cdc7 and Cdk9 kinase inhibitor (IC 50  values are 10 and 34 nM for Cdc7 in the presence of 1.5 μM ATP and Cdk9 respectively). Induces apoptosis in cancer cell lines. Shows synergistic antitumor effects  in vivo  with 5-fluorouracil (ab142387).\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:845538-12-7,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nMolecular weight:249.69 Da,\u003cbr\u003e\nMolecular formula:C12H12ClN3O,\u003cbr\u003e\nPubChem:11715766,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 10 mM,\u003cbr\u003e\nBiochemical name:PHA-767491 hydrochloride,\u003cbr\u003e\nBiological description:Potent Cdc7 and Cdk9 kinase inhibitor (IC50 values are 10 and 34 nM for Cdc7 in the presence of 1.5 μM ATP and Cdk9 respectively). Induces apoptosis in cancer cell lines. Shows synergistic antitumor effects in vivo with 5-fluorouracil (ab142387).,\u003cbr\u003e\nCanonical smiles:C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3.Cl,\u003cbr\u003e\nInChi:InChI=1S\/C12H11N3O.ClH\/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12;\/h1-2,4-5,7,15H,3,6H2,(H,14,16);1H,\u003cbr\u003e\nIUPAC Name:2-pyridin-4-yl-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one;hydrochloride\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847496650921,"sku":"ab144419","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab144419","provider":"Iright","version":"1.0","type":"link"}