{"product_id":"abcam-ab144598","title":"Abcam, ab144598, Epoxomicin, 20S proteasome inhibitor","description":"\u003cp\u003eSize: 100µg\u003cbr\u003e\nMW 554.7 Da, Purity \u0026gt;97%. Potent, selective, irreversible and cell-permeable 20S proteasome inhibitor (IC 50  = 4 nM). Predominantly inhibits the chymotrypsin-like activity. Anti-inflammatory and antitumor agent. Active  in vitro  and  in vivo .\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:134381-21-8,\u003cbr\u003e\nPurity:\u0026gt;97%,\u003cbr\u003e\nSource:Actinomyces sp.,\u003cbr\u003e\nMolecular weight:554.7 Da,\u003cbr\u003e\nMolecular formula:C28H50N4O7,\u003cbr\u003e\nPubChem:3035402,\u003cbr\u003e\nNature:Native,\u003cbr\u003e\nSolubility:Soluble in DMSO to 10 mM,\u003cbr\u003e\nBiochemical name:(2S,3S)-2-(Acetyl-methyl-amino)-3-methyl-pentanoic acid ((S)-1-{(R)-(R)-2-hydroxy-1-[(R)-3-methyl-1-((R)-2-methyl-oxiranecarbonyl)-butylcarbamoyl]-propylcarbamoyl}-2-methyl-butyl)-amide,\u003cbr\u003e\nBiological description:Potent, selective, irreversible and cell-permeable 20S proteasome inhibitor (IC50 = 4 nM). Predominantly inhibits the chymotrypsin-like activity. Anti-inflammatory and antitumor agent. Active in vitro and in vivo.,\u003cbr\u003e\nCanonical smiles:CCC(C)C(C(=O)NC(=O)C(C(C)O)NC(CC(C)C)C(=O)C1(CO1)C)NC(=O)C(C(C)CC)N(C)C(=O)C,\u003cbr\u003e\nIsomeric smiles:CC[C@H](C)[C@@H](C(=O)NC(=O)[C@H]([C@@H](C)O)NC(CC(C)C)C(=O)[C@]1(CO1)C)NC(=O)[C@H]([C@@H](C)CC)N(C)C(=O)C,\u003cbr\u003e\nInChi:InChI=1S\/C28H50N4O7\/c1-11-16(5)21(30-27(38)23(17(6)12-2)32(10)19(8)34)25(36)31-26(37)22(18(7)33)29-20(13-15(3)4)24(35)28(9)14-39-28\/h15-18,20-23,29,33H,11-14H2,1-10H3,(H,30,38)(H,31,36,37)\/t16-,17-,18+,20?,21-,22-,23-,28+\/m0\/s1,\u003cbr\u003e\nInChiKey:ZWCBKZGIPPDRLY-TXLQCSLMSA-N,\u003cbr\u003e\nIUPAC Name:(2S,3S)-2-[[(2S,3S)-2-[acetyl(methyl)amino]-3-methylpentanoyl]amino]-N-[(2S,3R)-3-hydroxy-2-[[4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]butanoyl]-3-methylpentanamide\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847419744425,"sku":"ab144598","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab144598","provider":"Iright","version":"1.0","type":"link"}