{"product_id":"abcam-ab144821","title":"Abcam, ab144821, Dorsomorphin dihydrochloride, AMP-kinase inhibitor","description":"\u003cp\u003eSize: 5mg \/ 10mg \/ 50mg\u003cbr\u003e\nMW 472.4 Da, Purity \u0026gt;99%. Potent, selective, reversible AMP-kinase inhibitor (K i  = 109 nM). BMP type I receptor inhibitor. Induce autophagy in cancer cells independent of AMPK inhibition. Promotes cardiomyogenesis in embryonic stem cells. Reduces hepcidin, VCAM-1 and ICAM-1 expression  in vivo.  .\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:1219168-18-9,\u003cbr\u003e\nPurity:\u0026gt;99%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:472.4 Da,\u003cbr\u003e\nMolecular formula:C24H27Cl2N5O,\u003cbr\u003e\nPubChem:49761481,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in water to 100 mM,\u003cbr\u003e\nBiochemical name:Dorsomorphin dihydrochloride,\u003cbr\u003e\nBiological description:Potent, selective, reversible AMP-kinase inhibitor (Ki = 109 nM). BMP type I receptor inhibitor. Induce autophagy in cancer cells independent of AMPK inhibition. Promotes cardiomyogenesis in embryonic stem cells. Reduces hepcidin, VCAM-1 and ICAM-1 expression in vivo.,\u003cbr\u003e\nCanonical smiles:C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3.Cl.Cl,\u003cbr\u003e\nInChi:InChI=1S\/C24H25N5O.2ClH\/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20;;\/h4-11,16-18H,1-3,12-15H2;2*1H,\u003cbr\u003e\nInChiKey:RJDVIJJQKMGPMV-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine;dihydrochloride\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847427248297,"sku":"ab144821","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab144821","provider":"Iright","version":"1.0","type":"link"}