{"product_id":"abcam-ab146695","title":"Abcam, ab146695, Ro 25-6981 maleate salt (mM\/ml), NR2B antagonist","description":"\u003cp\u003eSize: 20mM \/ mL\u003cbr\u003e\nMW 455.5 Da, Purity \u0026gt;98%. Potent, highly selective, activity-dependent blocker of NMDA receptors that contain the NR2B subunit (IC 50  values are 0.009 and 52 μM at NR1C\/NR2B and NR1C\/NR2A, respectively). Displays no significant activity at kainate\/AMPA receptors, Na +  and Ca 2+  channels at concentrations showing maximal protection in neurotoxicity tests. Neuroprotective actions  in vivo  and  in vitro .\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:1312991-76-6,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:455.5 Da,\u003cbr\u003e\nMolecular formula:C26H33NO6,\u003cbr\u003e\nPubChem:53250677,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nBiochemical name:Ro 25-6981 maleate,\u003cbr\u003e\nBiological description:Potent, highly selective, activity-dependent blocker of NMDA receptors that contain the NR2B subunit (IC50 values are 0.009 and 52 μM at NR1C\/NR2B and NR1C\/NR2A, respectively). Displays no significant activity at kainate\/AMPA receptors, Na+ and Ca2+ channels at concentrations showing maximal protection in neurotoxicity tests. Neuroprotective actions in vivo and in vitro.,\u003cbr\u003e\nCanonical smiles:CC(CN1CCC(CC1)CC2=CC=CC=C2)C(C3=CC=C(C=C3)O)O.C(=CC(=O)O)C(=O)O,\u003cbr\u003e\nIsomeric smiles:C[C@@H](CN1CCC(CC1)CC2=CC=CC=C2)[C@H](C3=CC=C(C=C3)O)O.C(=C\\C(=O)O)\\C(=O)O,\u003cbr\u003e\nInChi:InChI=1S\/C22H29NO2.C4H4O4\/c1-17(22(25)20-7-9-21(24)10-8-20)16-23-13-11-19(12-14-23)15-18-5-3-2-4-6-18;5-3(6)1-2-4(7)8\/h2-10,17,19,22,24-25H,11-16H2,1H3;1-2H,(H,5,6)(H,7,8)\/b;2-1-\/t17-,22+;\/m0.\/s1,\u003cbr\u003e\nInChiKey:FYJZEHCQSUBZDY-SEELMCCHSA-N,\u003cbr\u003e\nIUPAC Name:4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol;(Z)-but-2-enedioic acid\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847503302825,"sku":"ab146695","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab146695","provider":"Iright","version":"1.0","type":"link"}