{"product_id":"abcam-ab157219","title":"Abcam, ab157219, Anti-CTRL antibody [EPR11490(B)]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal CTRL antibody. Suitable for WB and reacts with Mouse, Rat, Human samples. Cited in 1 publication.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR11490(B),\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Mouse, Rat, Human,\u003cbr\u003e\nApplications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nThe CTRL protein also known as chymotrypsin-like protease CTRL-1 functions primarily as a serine protease. It exhibits a catalytic domain typical of the Chymotrypsin family of serine proteases. With a mass of approximately 29 kDa CTRL is expressed prominently in pancreatic tissue but can also be found in other tissues at lower levels. It plays a role in protein degradation by cleaving at specific amino acid sites.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe serine protease activity of CTRL contributes to the digestion process by breaking down protein chains into smaller peptides. It does not work alone but rather as part of a larger complex. This involvement makes it integral to maintaining protein homeostasis in the body. It's expressed in various cellular processes that require the precise breakdown of polypeptides emphasizing its importance in tissue maintenance and repair.\u003cbr\u003e\nPathways\u003cbr\u003e\nCTRL is involved in the proteolytic pathway facilitating the breakdown of dietary proteins into absorbable units. It collaborates closely with other proteases such as trypsin that complement its function by targeting different peptide bonds. Additionally CTRL takes part in cellular metabolism pathways where it assists in processing proteins needed for cellular activities.\u003cbr\u003e\nDysfunctional CTRL activity associates with digestive disorders such as pancreatitis. An imbalance in its activity can also contribute to the development of pancreatic insufficiencies. In these contexts CTRL interacts with proteins like elastase where altered activity levels can exacerbate tissue damage during inflammatory conditions. Understanding CTRL's precise role provides insights into potential therapeutic targets for managing certain pathologies.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850227863721,"sku":"ab157219","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab157219","provider":"Iright","version":"1.0","type":"link"}