{"product_id":"abcam-ab165727","title":"Abcam, ab165727, Recombinant Human FITM1 protein","description":"\u003cp\u003eSize: 10µg\u003cbr\u003e\nRecombinant Human FITM1 protein is a Human Full Length protein, in the 1 to 292 aa range, expressed in Wheat germ, suitable for ELISA, WB.\u003cbr\u003e\nKey facts\u003cbr\u003e\nExpression system:Wheat germ,\u003cbr\u003e\nTags:GST tag N-Terminus,\u003cbr\u003e\nApplications:WB, ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nBiologically active:No,\u003cbr\u003e\nAccession:A5D6W6,\u003cbr\u003e\nAnimal free:No,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nSpecies:Human,\u003cbr\u003e\nStorage buffer:pH: 8Constituents: 0.79% Tris HCl, 0.31% Glutathione\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Dry Ice, Appropriate short-term storage conditions--80°C, Appropriate long-term storage conditions--80°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nFITM1 also known as Fat Storage-Inducing Transmembrane Protein 1 functions as a lipid droplet protein involved in lipid storage. This protein identifies in mammals with a sequence mass around 29 kDa. It expresses heavily in adipose tissues and to a lesser extent in liver and muscle tissues. FITM1 plays an essential role in regulating lipid droplet formation within these tissues.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nFITM1 facilitates the storage of neutral lipids within cells contributing to overall lipid metabolism. It acts as part of a molecular complex that anchors triglycerides within lipid droplets enabling efficient lipid storage. Through this mechanism FITM1 participates in maintaining cellular lipid balance reflecting its significance in fat storage physiology.\u003cbr\u003e\nPathways\u003cbr\u003e\nFITM1 integrates within metabolic pathways associated with lipid processing and energy homeostasis. Two important pathways include the lipid metabolic pathway and the insulin signaling pathway. FITM1 operates alongside proteins like FITM2 and perilipin where they coordinate to manage lipid droplet dynamics thereby influencing cellular energy metabolism.\u003cbr\u003e\nFITM1 influences the development of metabolic syndromes such as obesity and non-alcoholic fatty liver disease (NAFLD). Dysregulation of FITM1 affects lipid storage capacity linking it to these conditions. FITM1 connects with proteins involved in these disorders including adiponectin and leptin which play significant roles in energy metabolism and homeostasis.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46843970715817,"sku":"ab165727","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab165727","provider":"Iright","version":"1.0","type":"link"}