{"product_id":"abcam-ab165954","title":"Abcam, ab165954, Recombinant Human FAM13C1 protein","description":"\u003cp\u003eSize: 10µg\u003cbr\u003e\nRecombinant Human FAM13C1 protein is a Human Full Length protein, in the 1 to 585 aa range, expressed in Wheat germ, suitable for ELISA, WB.\u003cbr\u003e\nKey facts\u003cbr\u003e\nExpression system:Wheat germ,\u003cbr\u003e\nTags:GST tag N-Terminus,\u003cbr\u003e\nApplications:WB, ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nBiologically active:No,\u003cbr\u003e\nAccession:Q8NE31,\u003cbr\u003e\nAnimal free:No,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nSpecies:Human,\u003cbr\u003e\nStorage buffer:pH: 8Constituents: 0.79% Tris HCl, 0.31% Glutathione\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Dry Ice, Appropriate short-term storage conditions--80°C, Appropriate long-term storage conditions--80°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nFAM13C1 also known as Family with Sequence Similarity 13 Member C1 is a protein with a molecular mass of approximately 115 kDa. This protein is primarily expressed in the pancreas and to some extent in adipose tissue. FAM13C1 resides in the cytoplasm and interacts with components of the cytoskeleton indicating a role in cellular architecture and signaling.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe protein FAM13C1 is involved in regulating glucose metabolism and insulin signaling. It forms part of a dynamic protein complex that modulates the function of metabolic pathways. Research suggests it influences the activity of enzymes linked to lipid metabolism which can affect energy storage and usage in cells. This function positions FAM13C1 as an important modulator of metabolic processes.\u003cbr\u003e\nPathways\u003cbr\u003e\nFAM13C1 plays a role in the insulin signaling pathway and the PI3K-Akt signaling pathway. Its function in these pathways ties it closely with proteins like PI3K and AKT which are critical for cellular growth metabolism and survival. FAM13C1’s interaction with these pathways highlights its contribution to both signaling and metabolic regulation in cells.\u003cbr\u003e\nFAM13C1 has been associated with type 2 diabetes and obesity. Alterations in this protein's function or expression may disrupt normal insulin signaling potentially leading to insulin resistance. Such disruption links FAM13C1 with proteins like IRS1 which also play roles in insulin signaling and metabolic homeostasis. This connection highlights FAM13C1's significance in metabolic disorders.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46843969503401,"sku":"ab165954","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab165954","provider":"Iright","version":"1.0","type":"link"}