{"product_id":"abcam-ab181737","title":"Abcam, ab181737, HRP Anti-Papain antibody","description":"\u003cp\u003eSize: 100µg\u003cbr\u003e\nGoat Polyclonal Papain antibody - conjugated to HRP. Suitable for WB and reacts with Papaya samples. Cited in 2 publications. Immunogen corresponding to Native Full Length Protein corresponding to Papaya Papain.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Goat,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nConjugation:HRP,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Papaya,\u003cbr\u003e\nApplications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Native Full Length Protein corresponding to Papaya Papain.P00784\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purity-IgG fraction, Purification technique-Ion exchange chromatography, Purification notes-Anti-Papain is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer., Storage buffer-Preservative: 0.01% Gentamicin sulphateConstituents: 1% BSA, 0.88% Sodium chloride, 0.424% Potassium phosphate solution, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nPapain also known as papaya proteinase I is a cysteine protease enzyme derived from the papaya plant. It exhibits a molecular weight of approximately 23.4 kDa. Papain is synthesized primarily in the fruit of the papaya and its enzyme activity depends on the presence of thiol groups. This protease is popular in various industrial applications due to its ability to cleave a wide range of peptide bonds facilitating protein breakdown. Disulfide bonds within papain help stabilize its structure allowing efficient substrate digestion under different conditions.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nPapain functions as a proteolytic enzyme aiding in the hydrolysis of proteins into peptides and amino acids. It is not part of a complex but rather operates independently to perform its function. Papain's broad proteolytic activity makes it effective in breaking down tough protein structures in organisms enhancing nutrient availability. The enzyme's activity finds use in meat tenderizing and has a role in certain cellular processes such as protein catabolism.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe enzyme plays a role in dietary protein digestion and degradation pathways. It interacts with other proteases like ficin and bromelain working synergistically to facilitate the denaturation and digestion of proteins. These proteases including papain contribute significantly to metabolic processes that involve protein turnover and nitrogen metabolism in various organisms. Papain substrates often include proteins that require further degradation for metabolic purposes.\u003cbr\u003e\nPapain's relevance is notable concerning inflammation and wound healing. Studies suggest that papain's proteolytic properties help in removing dead tissue and promoting new tissue formation benefiting chronic wounds and ulcers. Papain also shows potential in managing inflammatory conditions where its degradation of specific protein substrates can minimize inflammatory responses. Proteins like elastase may connect to papain's activity as it mediates tissue regeneration and inflammation resolution.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854464438441,"sku":"ab181737","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab181737","provider":"Iright","version":"1.0","type":"link"}