{"product_id":"abcam-ab195033","title":"Abcam, ab195033, Anti-Arginine (glcnac ) antibody [EPR18251]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal Arginine antibody. Suitable for WB and reacts with Modified Amino Acid samples. Cited in 13 publications.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR18251,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nApplications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis antibody was developed as part of a collaboration between Abcam and the lab of Dr. Feng Shao, National Institute of Biological Sciences (NIBS), Beijing.\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nArginine often referred to as ARG plays a central role in various biological processes. It is an amino acid with a molecular weight of about 174.2 Da. Arginine is expressed in multiple tissues including the liver and endothelium. It often serves as a precursor for the synthesis of various biomolecules such as nitric oxide. In scientific literature you may also encounter it under alternative spellings like 'arganine' or 'argenine' though these are less common.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nArginine contributes to protein synthesis and serves as a substrate for enzymes like nitric oxide synthase. It forms part of larger protein complexes and participates in metabolic pathways. Nitric oxide produced from arginine acts as a signaling molecule that modulates vascular function by inducing vasodilation. It also takes part in immune responses and has a role in cell division wound healing and hormone release.\u003cbr\u003e\nPathways\u003cbr\u003e\nArginine plays a significant role in the urea cycle and the nitric oxide signaling pathway. It interacts with proteins such as ornithine transcarbamylase in the urea cycle facilitating the removal of ammonia. Meanwhile in the nitric oxide pathway it collaborates with nitric oxide synthase to produce nitric oxide which affects smooth muscle relaxation and neurotransmission.\u003cbr\u003e\nArginine has connections to cardiovascular diseases and immune-associated conditions. The production of nitric oxide which involves arginine impacts cardiovascular health and its dysregulation can lead to hypertension. Additionally arginine metabolism influences conditions like arginase deficiency which affects the urea cycle. These conditions can involve other proteins such as ornithine transcarbamylase demonstrating the interlinked nature of arginine with various biological and pathological processes.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46852555145385,"sku":"ab195033","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab195033","provider":"Iright","version":"1.0","type":"link"}