{"product_id":"abcam-ab219866","title":"Abcam, ab219866, LY-333531 hydrochloride, protein kinase Cbeta inhibitor","description":"\u003cp\u003eSize: 250µg \/ 1mg\u003cbr\u003e\nMW 505 Da, Purity \u0026gt;98%. Potent, isozyme-selective inhibitor of protein kinase Cβ (PKCβ). Competitively inhibits PKCßI and PKCßII (IC 50  values are 4.7 and 5.9 nM respectively). 76- and 61-fold selective for inhibition of PKCßI and PKCßII in comparison to PKCα, respectively. Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src).\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:169939-93-9,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:505 Da,\u003cbr\u003e\nMolecular formula:C28H29ClN4O3,\u003cbr\u003e\nPubChem:9870785,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 20 mM,\u003cbr\u003e\nBiochemical name:Ruboxistaurin Hydrochloride,\u003cbr\u003e\nBiological description:Potent, isozyme-selective inhibitor of protein kinase Cβ (PKCβ). Competitively inhibits PKCßI and PKCßII (IC50 values are 4.7 and 5.9 nM respectively). 76- and 61-fold selective for inhibition of PKCßI and PKCßII in comparison to PKCα, respectively. Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src).,\u003cbr\u003e\nCanonical smiles:CN(C)CC1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl,\u003cbr\u003e\nIsomeric smiles:CN(C)C[C@@H]1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl,\u003cbr\u003e\nInChi:InChI=1S\/C28H28N4O3.ClH\/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24;\/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34);1H\/t18-;\/m0.\/s1,\u003cbr\u003e\nInChiKey:NYQIEYDJYFVLPO-FERBBOLQSA-N,\u003cbr\u003e\nIUPAC Name:(18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8,10,12,22,24,26-nonaene-3,5-dione;hydrochloride\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called 2156 LY-333,531 hydrochloride. 2156-250 is the same size as the 250 µg size of ab219866.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847495438505,"sku":"ab219866","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab219866","provider":"Iright","version":"1.0","type":"link"}