{"product_id":"abcam-ab235550","title":"Abcam, ab235550, Miransertib, pan-Akt inhibitor","description":"\u003cp\u003eSize: 5mg \/ 25mg\u003cbr\u003e\nMW 432.5 Da, Purity \u0026gt;98%. Allosteric, selective, non-ATP competitive pan-Akt inhibitor (IC 50  = 5.0, 4.5, and 16 nM for Akt1, Akt2, and Akt3, respectively). Selective for Akt isoforms over a panel of 303 other kinases. Binds to and inhibits the activity of AKT in a non-ATP competitive manner, which may result in the inhibition of the PI3K\/AKT signaling pathway. Orally bioavailable.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:1313881-70-7,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:432.5 Da,\u003cbr\u003e\nMolecular formula:C27H24N6,\u003cbr\u003e\nPubChem:53262401,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 159.92 mMSoluble in ethanol to 8.52 mM,\u003cbr\u003e\nBiochemical name:Miransertib,\u003cbr\u003e\nBiological description:Allosteric, selective, non-ATP competitive pan-Akt inhibitor (IC50 = 5.0, 4.5, and 16 nM for Akt1, Akt2, and Akt3, respectively). Selective for Akt isoforms over a panel of 303 other kinases. Binds to and inhibits the activity of AKT in a non-ATP competitive manner, which may result in the inhibition of the PI3K\/AKT signaling pathway. Orally bioavailable.,\u003cbr\u003e\nCanonical smiles:C1CC(C1)(C2=CC=C(C=C2)N3C4=C(C=CC(=N4)C5=CC=CC=C5)N=C3C6=C(N=CC=C6)N)N,\u003cbr\u003e\nInChi:InChI=1S\/C27H24N6\/c28-24-21(8-4-17-30-24)25-32-23-14-13-22(18-6-2-1-3-7-18)31-26(23)33(25)20-11-9-19(10-12-20)27(29)15-5-16-27\/h1-4,6-14,17H,5,15-16,29H2,(H2,28,30),\u003cbr\u003e\nInChiKey:HNFMVVHMKGFCMB-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenylimidazo[4,5-b]pyridin-2-yl]pyridin-2-amine\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called B1931 Miransertib. B1931-25 is the same size as the 25 mg size of ab235550.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847439241385,"sku":"ab235550","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab235550","provider":"Iright","version":"1.0","type":"link"}