{"product_id":"abcam-ab249257","title":"Abcam, ab249257, Anti-MAS1L antibody [EPR11440(B)] - BSA and Azide free","description":"\u003cp\u003eSize: 100µg \/ 1mg\u003cbr\u003e\nRabbit Recombinant Monoclonal MAS1L antibody. Carrier free. Suitable for IP, WB, Flow Cyt (Intra) and reacts with Human samples.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR11440(B),\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:Yes,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WB, Flow Cyt (Intra), IPSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nab249257 is the carrier-free version of\u003cbr\u003e\nab156018\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003cbr\u003e\nConjugation ready\u003cbr\u003e\nOur carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.\u003cbr\u003e\nUse our\u003cbr\u003e\nconjugation kits\u003cbr\u003e\nfor antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.\u003cbr\u003e\nCompatibility\u003cbr\u003e\nThis product is compatible with the Maxpar\u003cbr\u003e\nAntibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar\u003cbr\u003e\nis a trademark of Fluidigm Canada Inc.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nMAS1L sometimes referred to as MAS1-like is a protein encoded by the MAS1L gene. Its mass is approximately 37 kDa. This protein is expressed in various tissues including the central nervous system and certain peripheral tissues. MAS1L is an integral membrane protein and it localizes on the cell surface which indicates its potential involvement in signaling processes. As a G protein-coupled receptor it plays a role in transmitting signals across the cell membrane.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nMAS1L functions within the context of signal transduction. It engages in biological processes by potentially forming complexes with other proteins or molecules that facilitate signaling activities. This protein's ability to interact with G proteins suggests its involvement in activating downstream cellular responses influencing various cellular functions such as growth differentiation or communication between cells. The MAS1L's role in signaling implicates it in maintaining normal cellular activity and responding to environmental cues.\u003cbr\u003e\nPathways\u003cbr\u003e\nMAS1L engages in signaling cascades potentially linked to the renin-angiotensin system and other related pathways that influence cardiovascular functions. In the renin-angiotensin system similar receptors like the MAS1 receptor participate suggesting that MAS1L could share functional similarities. The renin-angiotensin pathway plays an important role in regulating blood pressure and fluid balance and any interaction involving MAS1L might contribute to these physiological processes.\u003cbr\u003e\nAbnormal expression or mutation of MAS1L could relate to cardiovascular diseases and neurological disorders. Dysfunctional signaling through MAS1L might contribute to the pathology of hypertension a condition in which the MAS1 receptor also plays a significant role highlighting potential overlap in their functional pathways. Furthermore disruptions in MAS1L activity might affect neurological functions linking it to conditions that compromise nervous system integrity.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46851904176297,"sku":"ab249257","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab249257","provider":"Iright","version":"1.0","type":"link"}