{"product_id":"abcam-ab282436","title":"Abcam, ab282436, Ro 08-2750","description":"\u003cp\u003eSize: 10mg\u003cbr\u003e\nMW 270.24 Da, Purity 98%. An antagonist of nerve growth factor (NGF) with binding ratio of 1:1, IC 50  = 1 μM. Selectively inhibits binding to p75NTR over TRKA147 at low concentrations. However, it can impair NGF binding to TrkA at higher concentrations (more than 5 mM).\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:37854-59-4,\u003cbr\u003e\nPurity:98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:270.24 Da,\u003cbr\u003e\nMolecular formula:C13H10N4O3,\u003cbr\u003e\nPubChem:17756791,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO (up to 2.7 mg\/mL),\u003cbr\u003e\nBiochemical name:7,10-Dimethyl-2,4-dioxo-2,3,4,10-tetrahydrobenzo[g]pteridine-8-carbaldehyde,\u003cbr\u003e\nBiological description:An antagonist of nerve growth factor (NGF) with binding ratio of 1:1, IC50 = 1 μM. Selectively inhibits binding to p75NTR over TRKA147 at low concentrations. However, it can impair NGF binding to TrkA at higher concentrations (more than 5 mM).,\u003cbr\u003e\nCanonical smiles:CC1=CC2=C(C=C1C=O)N(C3=NC(=O)NC(=O)C3=N2)C,\u003cbr\u003e\nInChi:InChI=1S\/C13H10N4O3\/c1-6-3-8-9(4-7(6)5-18)17(2)11-10(14-8)12(19)16-13(20)15-11\/h3-5H,1-2H3,(H,16,19,20),\u003cbr\u003e\nInChiKey:JDEMVNYMYPJJIM-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carbaldehyde\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847502778537,"sku":"ab282436","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab282436","provider":"Iright","version":"1.0","type":"link"}