{"product_id":"abcam-ab287109","title":"Abcam, ab287109, ML-385","description":"\u003cp\u003eSize: 5mg \/ 25mg\u003cbr\u003e\nMW 511.6 Da, Purity \u0026gt;98%. A potent and selective Nrf2 inhibitor (Nrf2; IC 50  = 1.9 μM). ML-385 blocks Nrf2 downstream target gene expression. ML-385 displays specificity and selectivity for NSCLC cells with KEAP1 mutation, which leads to gain of Nrf2 function.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:846557-71-9,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:511.6 Da,\u003cbr\u003e\nMolecular formula:C29H25N3O4S,\u003cbr\u003e\nPubChem:1383822,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:\u0026gt;25 mg\/ml in DMSO,\u003cbr\u003e\nBiochemical name:2-(1,3-benzodioxol-5-yl)-N-[5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]acetamide,\u003cbr\u003e\nBiological description:A potent and selective Nrf2 inhibitor (Nrf2; IC50 = 1.9 μM). ML-385 blocks Nrf2 downstream target gene expression. ML-385 displays specificity and selectivity for NSCLC cells with KEAP1 mutation, which leads to gain of Nrf2 function.,\u003cbr\u003e\nCanonical smiles:CC1=CC=CC=C1C(=O)N2CCC3=C2C=CC(=C3)C4=C(SC(=N4)NC(=O)CC5=CC6=C(C=C5)OCO6)C,\u003cbr\u003e\nInChi:InChI=1S\/C29H25N3O4S\/c1-17-5-3-4-6-22(17)28(34)32-12-11-20-15-21(8-9-23(20)32)27-18(2)37-29(31-27)30-26(33)14-19-7-10-24-25(13-19)36-16-35-24\/h3-10,13,15H,11-12,14,16H2,1-2H3,(H,30,31,33),\u003cbr\u003e\nInChiKey:LINHYWKZVCNAMQ-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:2-(1,3-benzodioxol-5-yl)-N-[5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]acetamide\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called B2605 ML-385. B2605-25 is the same size as the 25 mg size of ab287109.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847443239081,"sku":"ab287109","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab287109","provider":"Iright","version":"1.0","type":"link"}