{"product_id":"abcam-ab34522","title":"Abcam, ab34522, HRP Anti-Glucoamylase antibody","description":"\u003cp\u003eSize: 100µg\u003cbr\u003e\nGoat Polyclonal AMYG antibody - conjugated to HRP. Suitable for ELISA, WB and reacts with Rhizopus arrhizus samples.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Goat,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nConjugation:HRP,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Rhizopus arrhizus,\u003cbr\u003e\nApplications:WB, ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purity-IgG fraction, Purification technique-Ion exchange chromatography, Purification notes-Glucoamylase is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer., Storage buffer-Preservative: 0.01% Gentamicin sulphateConstituents: 1% BSA, 0.88% Sodium chloride, 0.424% Potassium phosphate solution, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nGlucoamylase also known as amyloglucosidase is an enzyme that plays a significant role in carbohydrate metabolism. It breaks down starch into glucose units by cleaving alpha-14-glycosidic and alpha-16-glycosidic bonds at the non-reducing ends. Glucoamylase has a molecular mass of approximately 58 kDa although this can vary slightly depending on the source. This enzyme is expressed mainly in the pancreas and small intestine where it aids in the digestion of dietary starch.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nGlucoamylase contributes to catabolic processes by facilitating the conversion of polysaccharides into simple sugars which are easier for cells to absorb and utilize. Glucoamylase often works in conjunction with other enzymes such as alpha-amylase and maltase acting synergistically to efficiently degrade complex carbohydrates. This collaborative action forms a multi-enzyme complex that maximizes starch conversion under physiological conditions.\u003cbr\u003e\nPathways\u003cbr\u003e\nGlucoamylase functions as an important part of carbohydrate metabolism especially the starch and sucrose metabolism pathway. In this context it helps provide glucose which acts as a primary energy source for cellular activities. By working closely with enzymes like hexokinase and phosphofructokinase glucoamylase ensures efficient continuity within the glycolysis pathway leading to optimal energy production. These cooperative interactions are essential for maintaining energy balance at the cellular level.\u003cbr\u003e\nDisturbances in glucoamylase activity can be associated with diabetes mellitus and some forms of malabsorption syndromes. In diabetes increased glucose levels can lead to complications if glucoamylase activity is not properly regulated. Moreover its interaction with insulin pathways further highlights the importance of maintaining proper enzyme function. Malabsorption syndromes may also result from inadequate glucoamylase levels leading to insufficient breakdown of dietary starches which can exacerbate digestive issues and nutrient deficiencies.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854456049833,"sku":"ab34522","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/abcam-ab34522","provider":"Iright","version":"1.0","type":"link"}