{"product_id":"biolegend-132402","title":"Biolegend, 132402, Purified anti-mouse CD62E (E-selectin) Antibody, 100μg","description":"\u003cp\u003eCD62E (also known as E-selectin, ELAM-1, and LECAM-1) is a 115 kD type I transmembrane protein and a member of the selectin family. CD62E is highly expressed on activated endothelial cells. CD62E is involved in leukocyte tethering and rolling on activated endothelium at inflammatory sites and may also play a role in tumor metastasis and angiogenesis. CD62E binds to both Sialyl Lewis X (CD15s) and PSGL-1 (CD162).\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Transfectant cells (29-564 aa) and recombinant protein (29-564 aa)\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Flow cytometry testing showed that clone W20055M does not affect binding of clone W20055P on target cells.\u003cbr\u003e\nRRID: AB_3097461 (BioLegend Cat. No. 132402)\u003cbr\u003e\nStructure: Member of the selectin family, 115 kD type I membrane protein; contains one C-type lectin domain and one EGF-like domain\u003cbr\u003e\nDistribution: Highly expressed on activated endothelial cells\u003cbr\u003e\nFunction: Involved in leukocyte tethering and rolling on activated endothelium at inflammatory sites, may also play a role in tumor metastasis and angiogenesis\u003cbr\u003e\nLigand\/Receptor: Sialyl Lewis X (CD15s) and PSGL-1 (CD162) bind to CD62E. Recently, CLA (cutaneous lymphocyte antigen) has also been reported to interact with CD62E\u003cbr\u003e\nCell Type: Endothelial cells\u003cbr\u003e\nBiology Area: Angiogenesis, Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nGene ID: 20339\u003cbr\u003e\nUniProt: View information about CD62E on UniProt.org\u003cbr\u003e\nClone: W20055M\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: E-selectin, ELAM-1, LECAM-1\u003cbr\u003e\nIsotype: Rat IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866419417257,"sku":"132402","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-132402","provider":"Iright","version":"1.0","type":"link"}