{"product_id":"biolegend-139903","title":"Biolegend, 139903, PE anti-mouse TCR Vα11.1, 11.2 Antibody, 25μg","description":"\u003cp\u003eVα11 T cell receptor (TCR Vα11) is a variant of TCR α chain and, along with TCR β chain, forms the TCR heterodimer. In association with the CD3 complex, TCR α\/β is responsible for antigen recognition through the interaction with MHC-peptide complex to initiate the T cell-mediated immune responses. The RR8-1 antibody is specific for b and d haplotypes of TCR Vα11.1 and Vα11.2, but not for Vα11.3. It does not react with a and c haplotypes of TCR Vα11.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse T-cell clone B10\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.06 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Jameson SC, et al. 1991. J. Immunol. 147:3185. (FC)\u003cbr\u003e\nRRID: AB_10640825 (BioLegend Cat. No. 139903) AB_10644000 (BioLegend Cat. No. 139904)\u003cbr\u003e\nStructure: Member of the immunoglobulin superfamily, Vα11 is a variant of the TCR α chain which associates with the TCR β chain to form the TCR heterodimer.\u003cbr\u003e\nDistribution: Subset of TCR αβ+ T cells.\u003cbr\u003e\nFunction: Recognition of peptides presented by MHC molecules, responsible for T cell mediated immune responses.\u003cbr\u003e\nLigand\/Receptor: MHC-peptide complex\u003cbr\u003e\nCell Type: T cells\u003cbr\u003e\nBiology Area: Adaptive Immunity, Immunology\u003cbr\u003e\nMolecular Family: TCRs\u003cbr\u003e\nGene ID: 21473\u003cbr\u003e\nUniProt: View information about TCR Valpha11.1 11.2 on UniProt.org\u003cbr\u003e\nClone: RR8-1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Vα11 T-cell receptor,T cell receptor alpha 11\u003cbr\u003e\nIsotype: Rat IgG2b, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866202427561,"sku":"139903","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-139903","provider":"Iright","version":"1.0","type":"link"}