{"product_id":"biolegend-142005","title":"Biolegend, 142005, PE anti-mouse CD355 (CRTAM) Antibody, 25μg","description":"\u003cp\u003eClass-I MHC-restricted T-cell associated molecule (CRTAM), designated as CD355, is an Ig domain like type I transmembrane receptor, which belongs to the nectin family. In the immune system, CRTAM is strictly expressed on activated NK cells and activated CD8-positive T cells. By binding its ligand Nectin-like molecule 2 (Necl2), CRTAM plays an important role in mediating cell adhesion and migration.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: CRTAM extracellular region-human IgG Fc fusion protein\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications (for relevant formats) include: Western blotting1.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Arase N, et al. 2005. Int. Immunol. 17:1227. (WB)\u003cbr\u003e\nRRID: AB_10896791 (BioLegend Cat. No. 142005) AB_10900439 (BioLegend Cat. No. 142006)\u003cbr\u003e\nStructure: 75 kD homodimer, nectin family, Ig superfamily\u003cbr\u003e\nDistribution: Activated NK cells and activated CD8-positive T cells\u003cbr\u003e\nFunction: Cell adhesion, migration\u003cbr\u003e\nLigand\/Receptor: Nectin-like molecule 2\u003cbr\u003e\nCell Type: NK cells, T cells\u003cbr\u003e\nBiology Area: Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Signal Transduction\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: 1. Takeuchi A, et al. 2009. J. Immunol. 183:4220. 2. Yeh JH, et al. 2008. Cell 132:846. 3. Arase N. 2005. Int. Immunol. 17:1227. 4. Boles KS, et al. 2005. Blood 106:779. 5. Galibert L, et al. 2005 J. Biol. Chem. 280:21955. 6. Kennedy J, et al. 2000 J. Leukoc. Biol. 67:725.\u003cbr\u003e\nGene ID: 54698\u003cbr\u003e\nUniProt: View information about CD355 on UniProt.org\u003cbr\u003e\nClone: 11-5\/CRTAM\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Class I-restricted T cell-associated molecule\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46860786401449,"sku":"142005","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-142005","provider":"Iright","version":"1.0","type":"link"}