{"product_id":"biolegend-148902","title":"Biolegend, 148902, Purified anti-mouse\/rat CD161f (NKPR1f) Antibody, 100μg","description":"\u003cp\u003eCD161, also known as NKRP1f, is mainly expressed on NK cells with little to no expression on T or B cells. NKRP1f on the surface of dendritic cells can bind to Clr-g expressed on activated T cells and result in production of IL-2 and proliferation of T cells. NKRP1f may also play a role in the formation of synapses between T cells and antigen presenting dendritic cells.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse, Rat\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: NKRP1f transfected YB2\/0 rat plasmacytoma cells.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nProduct Citations: Mortazavi F, et al. 2019. Bio Protoc. e3321:9. PubMed\u003cbr\u003e\nRRID: AB_2564270 (BioLegend Cat. No. 148902)\u003cbr\u003e\nStructure: CLR family, 24.7 kD, ITIM-less activation receptor\u003cbr\u003e\nDistribution: NK cells, dendritic cells\u003cbr\u003e\nFunction: Facilitates IL-2 production and proliferation of T cells and may contribute to the formation of immunological synapses.\u003cbr\u003e\nLigand\/Receptor: Clr-g\u003cbr\u003e\nCell Type: NK cells, Dendritic cells\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Signal Transduction\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Skálová T, et al. 2012. J. Immunol. 189:4881.2. Tian W, et al. 2005. Cell Immunol. 234:39. 3. Plougastel B, et al. 2001. Immunogenetics. 53:592. 4. Kveberg L, et al. 2011. Immunogenetics. 63:429.\u003cbr\u003e\nGene ID: 232408\u003cbr\u003e\nUniProt: View information about CD161f on UniProt.org\u003cbr\u003e\nClone: C8\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Killer cell lectin-like receptor subfamily B member 1F (Klrb1f), Nkr-p1f, Nkrp1-f, A630024B12Rik\u003cbr\u003e\nIsotype: Rat IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862951678121,"sku":"148902","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-148902","provider":"Iright","version":"1.0","type":"link"}