{"product_id":"biolegend-149615","title":"Biolegend, 149615, PE\/Dazzle™ 594 anti-mouse CD182 (CXCR2) Antibody, 25μg","description":"\u003cp\u003eCD182, also known as CXCR2, is a G-protein coupled receptor with seven transmembrane regions that is involved in chemotaxis, neutrophil activation, and angiogenesis. CXCR2 is expressed by neutrophils, basophils, a subset of T cells, monocytes, macrophages, natural killer (NK) and natural killer T cells (NKT). Its ligands are CXCL1, CXCL2, CXCL3, and CXCL5.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse CXCR2-transfected cells.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE\/Dazzle™ 594 under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nRRID: AB_2860708 (BioLegend Cat. No. 149615) AB_2860709 (BioLegend Cat. No. 149616)\u003cbr\u003e\nStructure: G-protein coupled receptor and seven transmembrane regions.\u003cbr\u003e\nDistribution: Neutrophils, basophils, subset of T cells, monocytes, macrophages, and natural killer (NK) cells.\u003cbr\u003e\nFunction: Chemotaxis, neutrophil activation, and angiogenesis.\u003cbr\u003e\nLigand\/Receptor: CXCL1, CXCL2, CXCL3, and CXCL5.\u003cbr\u003e\nCell Type: Basophils, Macrophages, Monocytes, Neutrophils, NK cells, T cells\u003cbr\u003e\nBiology Area: Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: CD Molecules, Cytokine\/Chemokine Receptors, GPCR\u003cbr\u003e\nAntigen References: 1. Spaan AN, et al. 2014. Nat. Commun. 5:5438. 2. Natsuaki Y, et al. 2014. Nat. Immunol. 15:1064. 3. Hsieh CY, et al. 2014. J. Immunol. 193:3693. 4. Diana J and Lehuen A. 2014. EMBO Mol. Med. 6:1090. 5. Stoolman JS, et al. 2014. J. Immunol. 193:564.\u003cbr\u003e\nGene ID: 12765\u003cbr\u003e\nUniProt: View information about CD182 on UniProt.org\u003cbr\u003e\nClone: SA045E1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: IL-8RB, GRO\/MGSA, Cmkar2\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866280546473,"sku":"149615","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-149615","provider":"Iright","version":"1.0","type":"link"}