{"product_id":"biolegend-156420","title":"Biolegend, 156420, PerCP\/Cyanine5.5 anti-mouse CD32 (Fcgr2) Antibody, 100μg","description":"\u003cp\u003eCD32 (Fcgr2) is a 40 kD transmembrane glycoprotein, member of the immunoglobulin superfamily. The extracellular region of CD32 consists of two Ig C-type domains that binds the Fc region from monomeric IgG with low affinity, but binds immune complexes efficiently. CD32 can mediate phagocytosis of immune complexes and modulate cell activation. CD32 is expressed by Macrophages, neutrophils, mast cells and B cells.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse CD32 transfected cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PerCP\/Cyanine5.5 under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. * PerCP\/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nRRID: AB_3106152 (BioLegend Cat. No. 156419) AB_3106152 (BioLegend Cat. No. 156420)\u003cbr\u003e\nStructure: 40 kD transmembrane glycoprotein, member of the immunoglobulin superfamily; extracellular region consists of two Ig C-type domains.\u003cbr\u003e\nDistribution: Macrophages, neutrophils, mast cells and B cells.\u003cbr\u003e\nFunction: Mediates phagocytosis of immune complexes, modulates cell activation.\u003cbr\u003e\nLigand\/Receptor: Binds Fc from monomeric IgG with low affinity, binds immune complexes efficiently.\u003cbr\u003e\nCell Type: B cells, Macrophages, Mast cells, Neutrophils\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules, Fc Receptors\u003cbr\u003e\nAntigen References: Negishi-Koga T, et al. 2015. Nat Commun. 6:6637 Yamada DH, et al. 2015. Immunity. 42:379 Clatworthy MR, et al. 2014. Nat Med. 20:1458 Li F and Ravetch JV. 2011. Science. 333:1030 Xiang Z, et al. 2007. Nat Immunol. 8:419\u003cbr\u003e\nGene ID: 14130\u003cbr\u003e\nUniProt: View information about CD32 on UniProt.org\u003cbr\u003e\nClone: S17012B\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Fcr-2, Fcr-3, Ly-17, LyM-1, Lym-1, fcRII, FcgRII, fcgr2b\u003cbr\u003e\nIsotype: Rat IgG2b, κ\u003cbr\u003e\nQ: How stable is PerCP\/Cyanine5.5 tandem as compared to PerCP alone?\u003cbr\u003e\nA: PerCP\/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866231656617,"sku":"156420","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-156420","provider":"Iright","version":"1.0","type":"link"}