{"product_id":"biolegend-157002","title":"Biolegend, 157002, Purified anti-mouse CD154 (CD40L) Antibody, 500μg","description":"\u003cp\u003eCD154 has been kown a 39 kD TNF superfamily member also known as CD40 ligand, gp39, T-BAM, TRAP, and Ly-62. CD154 is an accessory molecule expressed predominantly on activated CD4 + lymphocytes that bind CD40. CD154 plays an important role in T-B cell costimulation and Ig class switching.\u003cbr\u003e\n500μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: mCD40L-transfectants\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nProduct Citations: Garcia-Valtanen P, et al. 2022. Cell Rep Med. 3:100651. PubMed\u003cbr\u003e\nRRID: AB_2810425 (BioLegend Cat. No. 157002)\u003cbr\u003e\nStructure: A 39 kD TNF superfamily memeber\u003cbr\u003e\nDistribution: Surface activated CD4+ T cells,B cells, macrophages, dendritic cells, mast cells, NK cells, polymorphs, monocytes, and activated platelets.\u003cbr\u003e\nFunction: Survival signaling to CD40+ B cells and Ig class switching.\u003cbr\u003e\nLigand\/Receptor: CD40\u003cbr\u003e\nCell Type: B cells, Basophils, Dendritic cells, Fibroblasts, Macrophages, Mast cells, NK cells, Platelets, T cells\u003cbr\u003e\nBiology Area: Costimulatory Molecules, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nGene ID: 959\u003cbr\u003e\nUniProt: View information about CD154 on UniProt.org\u003cbr\u003e\nClone: SA047C3\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CD40L, gp39, TRAP, T-BAM, TNFSF5, CD40 Ligand\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866281529513,"sku":"157002","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-157002","provider":"Iright","version":"1.0","type":"link"}