{"product_id":"biolegend-159105","title":"Biolegend, 159105, APC anti-mouse CD289 (TLR9) Antibody, 25μg","description":"\u003cp\u003eTLR9 is a member of the toll-like receptor family that aids in recognition of pathogen associated molecular patterns (PAMPs). TLR9 recognizes unmethylated CpG sequences in DNA (ie. intracellular bacteria and DNA viruses). TLR9 signals through the MyD88 pathway leading to inflammatory cytokine production, especially production of type I interferons by pDCs.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Proprietary\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: ICFC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nRRID: AB_2876553 (BioLegend Cat. No. 159105) AB_2876553 (BioLegend Cat. No. 159106)\u003cbr\u003e\nDistribution: B cells, Dendritic cells, pDCs\u003cbr\u003e\nCell Type: B cells, Dendritic cells\u003cbr\u003e\nBiology Area: Bacterial proteins and Toxins, Immuno-Oncology, Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: CD Molecules, Innate Immune Signaling, Toll Like Receptors\u003cbr\u003e\nAntigen References: Onji M, et al. 2013. Nat. Commun. DOI: 10.1038\/ncomms2949 Krug A, et al. 2001. Eur J Immunol. 10:3026-37.\u003cbr\u003e\nGene ID: 81897\u003cbr\u003e\nUniProt: View information about CD289 on UniProt.org\u003cbr\u003e\nClone: S18025A\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nIsotype: Rat IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866255118505,"sku":"159105","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-159105","provider":"Iright","version":"1.0","type":"link"}