{"product_id":"biolegend-162705","title":"Biolegend, 162705, APC anti-mouse AhR Antibody, 25μg","description":"\u003cp\u003eThe aryl hydrocarbon receptor (AhR) is a basic helix-loop-helix transcription factor that is activated by multiple ligands such as TCDD. It is expressed in many immune cells and performs an important role in immune regulation. AhR is induced under Th17-polarizing conditions. In its inactive state, AhR is present in the cytoplasm, but upon ligand binding, it translocates to the nucleus. Activation of AhR is tightly controlled by ubiquitination, ligand metabolism, and AhR complex disruption.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: ICFC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nRRID: AB_3720526 (BioLegend Cat. No. 162705) AB_3720526 (BioLegend Cat. No. 162706)\u003cbr\u003e\nGene ID: 11622\u003cbr\u003e\nUniProt: View information about AhR on UniProt.org\u003cbr\u003e\nClone: W16012C\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: bHLHe76, aryl hydrocarbon receptor, Aryl hydrocarbon receptor, RP85\u003cbr\u003e\nIsotype: Rat IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866301255849,"sku":"162705","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-162705","provider":"Iright","version":"1.0","type":"link"}