{"product_id":"biolegend-164103","title":"Biolegend, 164103, PE anti-mouse CD170 Recombinant Antibody, 25μg","description":"\u003cp\u003eCD170, also known as Siglec-F, Siglec-5, is a member of the Sialic acid-binding Ig-like lectin family, type I single pass transmembrane protein, with 4 extracellular Ig-like domains and 2 ITIM motifs in the cytoplasmic domain; preferentially binds [alpha]-2,3-linked sialic acid. Siglec F is expressed in eosinophils, alveolar macrophages and intestinal microfold (M) cells and induces apoptosis of the lung eosinophils during allergic asthma.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Recombinant\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: This recombinant antibody clone is derived from clone S17007L.\u003cbr\u003e\nRRID: AB_2894437 (BioLegend Cat. No. 164103) AB_2894437 (BioLegend Cat. No. 164104)\u003cbr\u003e\nStructure: Member of the immunoglobulin superfamily, single pass transmembrane protein, forms a 140 kD dimer; cytoplasmic domain contains two ITIM motifs\u003cbr\u003e\nDistribution: Granulocytes, Monocytes, Macrophages, Lymphocytes, Dendritic cells, B cells, eosinophils.\u003cbr\u003e\nFunction: Inhibitory receptor, cell adhesion\u003cbr\u003e\nLigand\/Receptor: α2,3- and α2,6-linked sialic acid.\u003cbr\u003e\nGene ID: 8778\u003cbr\u003e\nUniProt: View information about CD170 on UniProt.org\u003cbr\u003e\nClone: QA20A11\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: OBBP2, CD33L2, OB-BP2\u003cbr\u003e\nIsotype: Rat IgG1, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866190598313,"sku":"164103","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-164103","provider":"Iright","version":"1.0","type":"link"}