{"product_id":"biolegend-167003","title":"Biolegend, 167003, APC anti-mouse CD157 (BST-1) Antibody, 25μg","description":"\u003cp\u003eCD157, also known as ADP-ribosyl cyclase 2, BST-1 (bone marrow stromal cell antigen 1), and BP-3 antigen, is an ectoenzyme member of the ADP-ribosyl cyclase family. It has a molecular weight between 40 - 46 kD and is a GPI-linked cell membrane glycoprotein which is expressed as a homodimer. CD157 is expressed by macrophages, neutrophils, bone marrow stromal cells, endothelial cells, follicular dendritic cells, and T and B cell progenitors prior to the rearrangement of the antigen receptors. Besides the ectoenzyme activity, it also plays a role in neutrophil migration and adhesion.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse CD157 transfected cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication Notes: Clone W21013C does not affect the binding of clone BP-3 on target cells.\u003cbr\u003e\nRRID: AB_3698934 (BioLegend Cat. No. 167003) AB_3698934 (BioLegend Cat. No. 167004)\u003cbr\u003e\nStructure: Member of the ADP-ribosyl cyclase family, ectoenzyme, 40-46 kD, glycosyl-phosphatidylinositol (GPI)- anchored membrane protein, present on the cell surface as a homodimer\u003cbr\u003e\nDistribution: Expressed by endothelial cells, follicular dendritic cells, cells from the myeloid lineage, and T and B cell precursors prior to the rearrangement of the antigen receptor. Expressed in many cell types from different tissues like the bone marrow, spleen, thymus, lung, kidney, and heart.\u003cbr\u003e\nFunction: Synthesizes cyclic ADP-ribose (cADPR)\u003cbr\u003e\nCell Type: B cells, Dendritic cells, Endothelial cells, T cells\u003cbr\u003e\nBiology Area: Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: Yamamoto-Katayama S, et al. 2002. J Mol Biol. 316:711-23. Funaro A, et al. 2009. Front Biosci. 14:929-43. Malavasi F, et al. 2006. Mol Med. 12:334-41. Vicari AP, et al. 1996. Int Immunol. 8:183-91.\u003cbr\u003e\nGene ID: 12182\u003cbr\u003e\nUniProt: View information about CD157 on UniProt.org\u003cbr\u003e\nClone: W21013C\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: cADPr hydrolase 2, Ly-65, BP-3, ADP-ribosyl cyclase 2, BST1\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866426757289,"sku":"167003","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-167003","provider":"Iright","version":"1.0","type":"link"}