{"product_id":"biolegend-201002","title":"Biolegend, 201002, Purified anti-rat CD68 Recombinant Antibody, 100μg","description":"\u003cp\u003eCD68, also known as macrosialin, is a 110 kD integral membrane glycoprotein from the lysosomal-associated membrane protein (LAMP) family. It is predominantly expressed on the intracellular lysosomes of monocytes and macrophages, and is considered a pan-macrophage marker in the rat. CD68 may have functions relating to phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Rat\u003cbr\u003e\nReported Reactivity: Bovine\u003cbr\u003e\nAntibody Type: Recombinant\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: ICFC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Clone QA20A71 can completely block the binding of parental clone to target cells. Both Cyto-Fast™ Fix\/Perm Buffer Set and True-Nuclear™ Transcription Factor Buffer Set work well. This clone does not react to human and mouse.\u003cbr\u003e\nRRID: AB_2936609 (BioLegend Cat. No. 201002)\u003cbr\u003e\nStructure: Lysosome-associated membrane glycoprotein; single-pass type I membrane protein, 110 kD\u003cbr\u003e\nDistribution: Macrophages, Langerhans cells, and at low levels on dendritic cells\u003cbr\u003e\nFunction: May involved in cell-cell interaction or cell-ligand interaction\u003cbr\u003e\nCell Type: Antigen-presenting cells, Dendritic cells, Langerhans cells, Leukocytes, Macrophages\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules, Innate Immune Signaling\u003cbr\u003e\nAntigen References: Dijkstra CD, et al. 1985. Immunology. 54:589-99. Damoiseaux JG, et al. 1994. Immunology. 83:140-7.\u003cbr\u003e\nGene ID: 287435\u003cbr\u003e\nUniProt: View information about CD68 on UniProt.org\u003cbr\u003e\nClone: QA20A71\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Macrosialin, GP110, LAMP4, Scavenger Receptor D1 (SR-D1)\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866194071721,"sku":"201002","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-201002","provider":"Iright","version":"1.0","type":"link"}