{"product_id":"biolegend-251102","title":"Biolegend, 251102, Purified anti-rat CD161 Recombinant Antibody, 100μg","description":"\u003cp\u003eQA19A15 recombinant monoclonal antibody recognizes the rat killer cell lectin-like receptor subfamily B member1 protein, also known as CD161. CD161 is expressed on rat NK cells and T cell subpopulations, activated monocytes, and dendritic cells. CD161 molecules are C-type lectin-like receptors that can either activate (CD161a) or inhibit (CD161b) effector leucocyte responses, eg, cytotoxicity or cytokine production, against target cells which express C-type lectin-like related (Clr) molecules.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Rat\u003cbr\u003e\nAntibody Type: Recombinant\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2894684 (BioLegend Cat. No. 251102)\u003cbr\u003e\nStructure: CD161 is a 233 amino acid ~60 kDa homodimers, type II single pass protein containing a single C-type lectin domain.\u003cbr\u003e\nDistribution: NK cells, subset of T cells, dendritic cells, activated monocytes.\u003cbr\u003e\nFunction: NKR-P1a is a NK cell-activating receptor; NKR-P1b is a NK cell-inhibitory receptor.\u003cbr\u003e\nLigand\/Receptor: LLT1-ligand lectin like transcript 1; KLR-killer cell lectin like receptor.\u003cbr\u003e\nCell Type: Dendritic cells, Monocytes, NK cells, T cells\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Innate Immunity, Signal Transduction\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: Chambers WH, et al. 1989. J Exp Med. 169:1373. Brink M, et al. 1990. J Exp Med. 171:197. Li J, et al. 2003. Int Immunol. 15:411.\u003cbr\u003e\nGene ID: 362443\u003cbr\u003e\nUniProt: View information about CD161 on UniProt.org\u003cbr\u003e\nClone: QA19A15\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CD161, NKR-P1, CD161a\/CD161b, NKR-P1a\/KLRB1a\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866186731689,"sku":"251102","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-251102","provider":"Iright","version":"1.0","type":"link"}