{"product_id":"biolegend-260166","title":"Biolegend, 260166, GMP PE anti-human CD24 Antibody, 100tests","description":"\u003cp\u003eCD24 is a 35-45 kD glycosylphosphatidylinositol (GPI)-linked protein also known as heat stable antigen (HSA), BA-1, Ly-52, and nectadrin. It is expressed on the surface of B cells (but not plasma cells), granulocytes, follicular dendritic cells, and epithelial cells. CD24 may play a role in the regulation of B-cell proliferation and maturation. CD24 crosslinking induces a Ca 2+ flux in mature B cells. CD24 has been shown to interact with CD62P (P-selectin).\u003cbr\u003e\n100tests\u003cbr\u003e\nReactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w\/v) BSA (origin USA) and a stabilizer\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: 200 µg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats) include: immunofluorescence microscopy3.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Schlossman S, et al. Eds. 1995. Leukocyte Typing V:White Cell Differentiation Antigens. Oxford University Press. New York. McMichael A, et al. 1987. Leucocyte Typing III. Oxford University Press. New York. Yang GP, et al. 1999. Nucleic Acids Research 27:1517. (IF) Kristiansen G, et al. 2003. Clin. Cancer Res. 9:4906. (FC)\u003cbr\u003e\nDisclaimer: GMP RUO Flow Cytometry Antibodies. BioLegend GMP RUO fluorophore conjugated antibodies are manufactured in a dedicated GMP facility and compliant with ISO 13485:2016. For research use only. Not for use in diagnostic or therapeutic procedures. Our processes include: Batch-to-batch consistency Material traceability Documented procedures Documented employee training Equipment maintenance and monitoring records Lot-specific certificates of analysis Quality audits per ISO 13485:2016 QA review of released products\u003cbr\u003e\nStructure: GPI-linked glycoprotein, 35-45 kD\u003cbr\u003e\nDistribution: B cells, granulocytes, epithelial cells\u003cbr\u003e\nFunction: B cell proliferation and differentiation\u003cbr\u003e\nLigand\/Receptor: CD62P (P-Selectin)\u003cbr\u003e\nCell Type: B cells, Epithelial cells, Granulocytes\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Schlossman S, et al. Eds. 1995. Leukocyte Typing V. Oxford University Press. New York.\u003cbr\u003e\nGene ID: 100133941\u003cbr\u003e\nUniProt: View information about CD24 on UniProt.org\u003cbr\u003e\nClone: ML5\u003cbr\u003e\nWorkshop: V CD24.5\u003cbr\u003e\nOther Names: Ly-52, Heat Stable Antigen (HSA), Nectadrin, BA-1\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866526306473,"sku":"260166","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-260166","provider":"Iright","version":"1.0","type":"link"}