{"product_id":"biolegend-260316","title":"Biolegend, 260316, GMP Pacific Blue™ anti-human CD5 Antibody, 100tests","description":"\u003cp\u003eCD5, also known as Leu-1, Ly-1 and T1, is a 67 kD single chain type I glycoprotein that is a member of the scavenger receptor superfamily. CD5 is expressed on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-CLL), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions. One of its ligands is CD72.\u003cbr\u003e\n100tests\u003cbr\u003e\nReactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Human T-acute lymphoblastic leukemia (ALL) cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w\/v) BSA (origin USA) and a stabilizer.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Pacific Blue™ under optimal conditions.\u003cbr\u003e\nConcentration: 400.0 µg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. * Pacific Blue™ has a maximum emission of 455 nm when it is excited at 405 nm. Prior to using Pacific Blue™ conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses\u003cbr\u003e\nExcitation Laser: Violet Laser (405 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats): immunoprecipitation1,3,4 and immmunohistochemical staining of frozen and formalin-fixed paraffin-embedded sections2,3,5.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): McAlister MS, et al. 1998. Protein Eng. 11:847. (IP) Butmarc JR, et al. 1998. Am. J. Clin. Pathol. 109:682. (IHC) Engleman EG, et al. 1981. Proc. Natl. Acad. Sci. USA 78:1791. (IHC, IP) Ledbetter JA, et al. 1981. J. Exp. Med. 153:310. (FC, IP) Warnke R and Levy R. 1980. J. Histochem. Cytochem. 28:771. (IHC)\u003cbr\u003e\nDisclaimer: GMP RUO Flow Cytometry Antibodies. BioLegend GMP RUO fluorophore conjugated antibodies are manufactured in a dedicated GMP facility and compliant with ISO 13485:2016. For research use only. Not for use in diagnostic or therapeutic procedures. Our processes include: Batch-to-batch consistency Material traceability Documented procedures Documented employee training Equipment maintenance and monitoring records Lot-specific certificates of analysis Quality audits per ISO 13485:2016 QA review of released products\u003cbr\u003e\nStructure: Scavenger receptor superfamily, 67 kD\u003cbr\u003e\nDistribution: Thymocytes, T cells, and subsets of B and dendritic cells.\u003cbr\u003e\nFunction: Modulates TCR and BCR signaling, involved in thymocyte maturation and T-B cell interaction\u003cbr\u003e\nLigand\/Receptor: CD72\u003cbr\u003e\nCell Type: B cells, Dendritic cells, T cells, Thymocytes\u003cbr\u003e\nBiology Area: Costimulatory Molecules, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Kipps T. 1989. Adv. Immunol. 47:117. 2. Resnick D, et al. 1994. Trends Biochem. Sci. 1:5. 3. Wood GS and Freudenthal PS. 1992. Am. J. Pathol. 141:789.\u003cbr\u003e\nGene ID: 921\u003cbr\u003e\nUniProt: View information about CD5 on UniProt.org\u003cbr\u003e\nClone: L17F12\u003cbr\u003e\nWorkshop: II T7\u003cbr\u003e\nOther Names: Leu-1, Ly-1, T1, Tp67, Leu1\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866525061289,"sku":"260316","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-260316","provider":"Iright","version":"1.0","type":"link"}