{"product_id":"biolegend-302703","title":"Biolegend, 302703, FITC anti-human CD26 Antibody, 25tests","description":"\u003cp\u003eCD26 is a 110 kD type II membrane protein also known as ADA-binding protein and dipeptidyl peptidase IV (DPPIV). It is a member of the peptidase and ectoenzyme family. CD26 is expressed on the membrane of mature thymocytes, T lymphocytes (upregulated upon activation), B cells, NK cells, and macrophages. CD26 cleaves off N-terminal X-Pro and X-Ala dipeptides from polypeptides. It plays an integral role as a costimulatory molecule in T cell activation. CD26 may interact with extracellular matrix proteins such as fibronectin or collagen, CD45 and ADA.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Press. London. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.\u003cbr\u003e\nProduct Citations: Fu H, et al. 2023. Regen Ther. 22:7. PubMed Musvosvi M, et al. 2023. Nat Med. 29:258. PubMed Gur C, et al. 2022. Cell. 185:1373. PubMed Wragg KM, et al. 2020. Cell Reports. 31(11):107773. PubMed Xin Y, et al. 2017. Exp Cell Res. 10.1016\/j.yexcr.2017.04.021. PubMed Tardif V, et al. 2019. Nat Commun. 10:823. PubMed Park J, et al. 2016. Proc Natl Acad Sci U S A. 113: 4482-4487. PubMed Lo ST, et al. 2021. Mol Imaging Biol. 23:230. PubMed Borrelli MR, et al. 2020. Aesthet Surg J. 369:40. PubMed Pfaender S, et al. 2020. Nat Microbiol. 1.131944444. PubMed Stoyanova T, et al. 2013. Proc Natl Acad Sci U S A. 110:20111. PubMed Khuzwayo S, et al. 2021. Front Immunol. 12:631410. PubMed Henry G, et al. 2017. Prostate. 77:1344. PubMed Angueira AR, et al. 2021. Nat Metab. 3:469. PubMed Jiang J, et al. 2016. Sci Rep. 6: 32320. PubMed\u003cbr\u003e\nRRID: AB_314288 (BioLegend Cat. No. 302704)\u003cbr\u003e\nStructure: Peptidases and ectoenzyme families, type II glycoprotein, 110 kD\u003cbr\u003e\nDistribution: Thymocyte subset, memory T cells, B cells, NK cells, epithelial cells, macrophages\u003cbr\u003e\nFunction: Dipeptidyl peptidase, T cell costimulation, HIV entry\u003cbr\u003e\nLigand\/Receptor: Adenosine-deaminase, collagen\u003cbr\u003e\nCell Type: B cells, Epithelial cells, Macrophages, NK cells, T cells, Thymocytes\u003cbr\u003e\nBiology Area: Costimulatory Molecules, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Kameoka J, et al. 1993. Science 261:466. 2. Dang N, et al. 1990. J. Exp. Med. 172:649.\u003cbr\u003e\nGene ID: 1803\u003cbr\u003e\nUniProt: View information about CD26 on UniProt.org\u003cbr\u003e\nClone: BA5b\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nWorkshop: VI N-L078\u003cbr\u003e\nOther Names: ADA-binding protein, DPP IV ectoenzyme, EC 3.4.14.5, DPP4\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862899282089,"sku":"302703","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-302703","provider":"Iright","version":"1.0","type":"link"}