{"product_id":"biolegend-307815","title":"Biolegend, 307815, Spark Violet™ 423 anti-human IgD Antibody, 25tests","description":"\u003cp\u003eIgD, a member of the immunoglobulin (Ig) family, is expressed in naïve B cells. It has 3 Ig-like domains and exists in a transmembrane and a soluble form. In general, IgD is not secreted and usually its expression is lost after the Ig isotype switch. After antigen binding, IgD signals through the CD79a\/CD79b (Igα\/Igβ) heterodimer, resulting in the activation of the B cell. (BioLegend Website)\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Native human IgD protein (full length)\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Spark Violet™ 423 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. * Spark Violet™ 423 has a maximum excitation of 400 nm and a maximum emission of 415 nm.\u003cbr\u003e\nExcitation Laser: Violet Laser (405 nm)\u003cbr\u003e\nApplication Notes: This clone does not cross react with mouse tissues.\u003cbr\u003e\nRRID: AB_2936558 (BioLegend Cat. No. 307815) AB_2936558 (BioLegend Cat. No. 307816)\u003cbr\u003e\nDistribution: Naïve B cells\u003cbr\u003e\nFunction: Antigen binding, B cell activation\u003cbr\u003e\nCell Type: B cells\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nAntigen References: Geisberger R, et al. 2006. Immunology. 118:429-37. Weller S, et al. 2005. Eur J Immunol. 35:2789-92. Brandtzaeg P \u0026amp; Johansen FE. 2005. Immunol Rev. 206:32-63.\u003cbr\u003e\nGene ID: 3495\u003cbr\u003e\nUniProt: View information about IgD on UniProt.org\u003cbr\u003e\nClone: W18340F\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Ig delta chain C region\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866340479145,"sku":"307815","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-307815","provider":"Iright","version":"1.0","type":"link"}