{"product_id":"biolegend-316704","title":"Biolegend, 316704, FITC anti-human TCR Vβ5 related subset Antibody, 100tests","description":"\u003cp\u003eThe Vβ5 TCR is a variant of the TCR β chain. It belongs to Ig superfamily and is expressed by a subset of peripheral blood T cells and some T cell clones. TCR Vβ5 has been reported to recognize some staphylococcus bacterial superantigens. MEM-262 antibody reacts with a variant of the TCR β chain which is expressed on HPB-ALL cells (known expressing TCR Vβ5.3). But the subpopulation of peripheral blood T cells recognized by this antibody is reported larger than other anti-TCR Vβ5.3 antibodies.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Human thymoma cell line HPB-ALL\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats) include: immunoprecipitation, Western blotting, and activation of T cells Vß5 related subset.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Pavlistova D, et al. 2003. Immunol. Lett. 88:105.\u003cbr\u003e\nRRID: AB_528957 (BioLegend Cat. No. 316704)\u003cbr\u003e\nStructure: Ig superfamily\u003cbr\u003e\nDistribution: T cell subset\u003cbr\u003e\nFunction: Antigen recognition, activation of TCR Vβ5 bearing T cells\u003cbr\u003e\nLigand\/Receptor: Some staphylococcus superantigens bound to MHC\u003cbr\u003e\nCell Type: T cells, Tregs\u003cbr\u003e\nBiology Area: Adaptive Immunity, Immunology\u003cbr\u003e\nMolecular Family: TCRs\u003cbr\u003e\nAntigen References: 1. Pavlistova D, et al. 2003. Immunol. Lett. 88:105 2. Kappler T, et al. 1989. Science 244:811 3. Fernandez MM, et al. 2006. Mol. Immunol. 43:927\u003cbr\u003e\nGene ID: NA\u003cbr\u003e\nUniProt: View information about TCR Vbeta5 on UniProt.org\u003cbr\u003e\nClone: MEM-262\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: T Cell Receptor Vβ5\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866464211113,"sku":"316704","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-316704","provider":"Iright","version":"1.0","type":"link"}