{"product_id":"biolegend-326002","title":"Biolegend, 326002, Purified anti-human CD84 Antibody, 100μg","description":"\u003cp\u003eCD84 is a 64-82 kD glycoprotein. It is a member of the SLAM (CD150) family, a CD2 subset of the Ig superfamily, also known as SLAMF5 or Ly9b. CD84 is expressed on B cells, monocytes, thymocytes, subset of (preferentially on CD45RO+) T cells, and platelets. CD84 functions as a homophilic adhesion molecule and enhances T cell activation and cytokine production. The antibody CD84.1.21 is able to enhance CD3 induced IFN-γ production and partially block CD84-Ig binding to lymphocytes.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: African Green, Baboon, Cynomolgus, Rhesus\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: 300.19 cell line transfected with the CD84 full-length DNA\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested IP - Reported in the literature, not verified in house\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Additional reported (for the relevant formats) applications include: immunoprecipitation2, and enhancing CD3 induced IFN-? production1 and partially block CD84-Ig binding to lymphocytes1.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Martin M, et al. 2001. J. Immunol. 167:3668. Sayós J, et al. 2001. Blood 97:3867. Morra M, et al. 2001. EMBO 20:5840. Morra M, 2001. J. Biol. Chem. 276:36809. Romero X, et al. 2004. Tissue Antigens 64:132.\u003cbr\u003e\nProduct Citations: Baskar R, et al. 2022. Cell Rep Methods. 2:. PubMed\u003cbr\u003e\nRRID: AB_830813 (BioLegend Cat. No. 326002)\u003cbr\u003e\nStructure: 64-82 kD glycoprotein, CD2 subset of Ig superfamily, SLAM family\u003cbr\u003e\nDistribution: B cells, monocytes, thymocytes, platelets, subset of (preferentially on CD45RO+) T cells\u003cbr\u003e\nFunction: Homophilic adhesion, T cell activation\u003cbr\u003e\nLigand\/Receptor: CD84\u003cbr\u003e\nCell Type: B cells, Monocytes, Platelets, T cells, Thymocytes\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: 1. de la Fuente MA, et al. 1997. Blood 90 (6):2398. 2. Tangye SG, et al. 2002. Eur. J. Immunol. 32(6):1640. 3. Tangye SG, et al. 2003. J. Immunol. 171:2485. 4. Martin M, et al. 2001. J. Immunol. 167:3668.\u003cbr\u003e\nGene ID: 8832\u003cbr\u003e\nUniProt: View information about CD84 on UniProt.org\u003cbr\u003e\nClone: CD84.1.21\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Ly9b, SLAMF5, GR6\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862990704809,"sku":"326002","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-326002","provider":"Iright","version":"1.0","type":"link"}