{"product_id":"biolegend-328505","title":"Biolegend, 328505, PE anti-human CD102 (ICAM-2) Antibody, 25tests","description":"\u003cp\u003eCD102 is a 55 kD type I transmembrane glycoprotein, belongs to immunoglobulin superfamily, also known as Intercellular Adhesion Molecule-2, or ICAM-2. CD102 is constitutively expressed on vascular endothelial cells, some lymphocytes, monocytes, and platelets. CD102 is thought to be involved in lymphocyte recirculation and in costimulation of immune response. CD102 is a counter receptor of LFA-1 (CD11a\/CD18), DC-SIGN and MAC-1.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: African Green, Baboon, Cynomolgus, Rhesus\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: ICAM-2 cDNA transfected COS cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications: immunoprecipitation(1), blocking the interaction between ICAM-2 and LFA-1(1), immunohistochemical staining(2) of frozen tissue sections\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): DeFougerolles AR,et al.1991.J. Exp.Med.174:253. Van Herpen CML,et al.2005.Clin. Cancer Res.11:1899\u003cbr\u003e\nProduct Citations: Suzuki D, et al. 2020. Stem Cell Reports. 14:49. PubMed Agostinis C, et al. 2019. Int J Mol Sci. 1.947222222. PubMed\u003cbr\u003e\nRRID: AB_2295682 (BioLegend Cat. No. 328505) AB_2122200 (BioLegend Cat. No. 328506)\u003cbr\u003e\nStructure: 55 kD type I transmembrane glycoprotein, Ig superfamily\u003cbr\u003e\nDistribution: Vascular endothelial cells, lymphocytes, monocytes, platelets\u003cbr\u003e\nFunction: Adhesion, costimulation\u003cbr\u003e\nLigand\/Receptor: LFA-1, DC-SIGN, MAC-1\u003cbr\u003e\nCell Type: Endothelial cells, Lymphocytes, Monocytes, Platelets\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: 1.Weber KSC, et al.2004.Inflammation.28:177. 2.Barclay A, et al.1997 The Leukoycte Antigen FactsbookAcademic Press. 3. Casasnovas JM, et al.1999.P. Natl. Acad. Sci. USA96:3017. 4. Diamonds MS, et al.1990. J. Cell Biol.111:3129.\u003cbr\u003e\nGene ID: 3384\u003cbr\u003e\nUniProt: View information about CD102 on UniProt.org\u003cbr\u003e\nClone: CBR-IC2\/2\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nWorkshop: V BP363\u003cbr\u003e\nOther Names: Intercellular Adhesion Molecule-2, ICAM-2\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862970060969,"sku":"328505","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-328505","provider":"Iright","version":"1.0","type":"link"}