{"product_id":"biolegend-332304","title":"Biolegend, 332304, PE anti-human CD352 (NTB-A) Antibody, 100tests","description":"\u003cp\u003eNTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2\/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Recombinant human CD352 protein\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC- Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nRRID: AB_2890763 (BioLegend Cat. No. 332303) AB_2890763 (BioLegend Cat. No. 332304)\u003cbr\u003e\nStructure: Type I transmembrane tyrosine-phosphorylated glycoprotein, CD2\/CD150 subfamily, 60 kD\u003cbr\u003e\nDistribution: NK cells, T cells, B cells\u003cbr\u003e\nFunction: CD28 independent T cell costimulation, induction of NK cell cytotoxicity, regulation of B cell tolerance\u003cbr\u003e\nLigand\/Receptor: NTBA\u003cbr\u003e\nAntigen References: 1. Yigit B, et al. 2019. Cancer Immunol. Res. 10.1158\/2326-6066 2. Wu N, et al. 2016. Nature Immunol. 17, 387-396 3. Radomir L, et al. 2017. J. Immunol. 199(8) 2745-2757\u003cbr\u003e\nGene ID: 114836\u003cbr\u003e\nUniProt: View information about CD352 on UniProt.org\u003cbr\u003e\nClone: W19035D\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: SLAMF6, LY108, TCOM, SF2000, NTBA\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866342248617,"sku":"332304","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-332304","provider":"Iright","version":"1.0","type":"link"}