{"product_id":"biolegend-333008","title":"Biolegend, 333008, PE anti-human CD85k (ILT3) Antibody, 100tests","description":"\u003cp\u003eCD85k, known as Immunoglobulin-like transcript (ILT) 3, is an inhibitory receptor expressed by dendritic cells and a subset of white blood cells called monocytes.  ILT3, also known as Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4) and Leukocyte Immunoglobulin-like Receptor 5 (LIR-5), is a type I membrane protein that contains cytoplasmic ITIM motifs and is involved in the down-regulation of immune responses. Expression of ILT3 is up-regulated on tolerogenic dendritic cells.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: ILT3 fusion protein\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nProduct Citations: Mitsune A, et al. 2021. Respir Res. 22:232. PubMed Su R, et al. 2020. Cancer Cell. 38(1):79-96.e11. PubMed Richardson JR, et al. 2018. Front Immunol. 2.182638889. PubMed Wierzbinska JA, et al. 2020. Genome Med. 12:29. PubMed Paavola KJ, et al. 2021. Cancer Immunol Res. 9:1283. PubMed\u003cbr\u003e\nRRID: AB_1027680 (BioLegend Cat. No. 333007) AB_2136645 (BioLegend Cat. No. 333008)\u003cbr\u003e\nStructure: Immunoglobulin superfamily\u003cbr\u003e\nDistribution: Monocytes, Macrophages, and Dendritic Cells\u003cbr\u003e\nCell Type: Dendritic cells, Macrophages, Monocytes\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: Cella M, et al. 1997. J Exp Med. 185:1743-51. Penna G, et al. 2005. Blood. 5:2044.\u003cbr\u003e\nGene ID: 11006\u003cbr\u003e\nUniProt: View information about CD85k on UniProt.org\u003cbr\u003e\nClone: ZM4.1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Immunoglobulin-like transcript (ILT) 3, CD85k, Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4), Leukocyte Immunoglobulin-like Receptor 5 (LIR-5)\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46864110321833,"sku":"333008","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-333008","provider":"Iright","version":"1.0","type":"link"}